溴代丙烷
溴代丙烷用途
用于合成医药、农药、染料、香料等
【用途二】
用于有机合成及制药工业
【用途三】
1-溴丙烷作为一种有机合成原料，在农药上用于合成有机磷杀虫杀螨剂硫丙磷、丙硫磷、丙溴磷等，也可用于医药、染料、香料工业，以及作为格氏试剂原料。
【用途四】
用于医药、农药、染料、香料等制造，还用作Grignard试剂的原料，药物丙硫硫胺，丙磺舒的中间体。
【用途五】
用于医药；农药；染料；香料等制造，还用作Grignard试剂的原料，药物丙硫硫胺，丙磺舒的中间体。
溴代丙烷名称
[ CAS 号 ]:
106-94-5
[ 中文名 ]:
溴代正丙烷
[ 英文名 ]:
1-Bromopropane
[中文别名 ]:
[英文别名 ]:
- 1-propyl bromide
- N-PROPYLBROMIDE(BROMOPROPANE)
- 1,3-Br-propane
- Propane, 1-bromo-
- n-C3H7Br
- 1-Bromopropane
- UNII-Y9746DNE68
- 1-BROMOPROPANE FOR SYNTHESIS
- EINECS 203-445-0
- bromo propane
溴代丙烷物理化学性质
[ 密度 ]:
1.3±0.1 g/cm3
[ 沸点 ]:
71.7±3.0 °C at 760 mmHg
[ 熔点 ]:
-110 °C
[ 分子式 ]:
C3H7Br
[ 分子量 ]:
122.992
[ 闪点 ]:
-4.5 ºC
[ 精确质量 ]:
121.973106
[ LogP ]:
2.21
[ 外观性状 ]:
无色透明液体
[ 蒸汽密度 ]:
4.3 (vs air)
[ 蒸汽压 ]:
133.4±0.1 mmHg at 25°C
[ 折射率 ]:
1.432
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放
[ 稳定性 ]:
Stability Flammable - note low flash point. Incompatible with strong oxidizing agents, strong bases.
[ 水溶解性 ]:
2.5 g/L (20 ºC)
溴代丙烷MSDS
溴代丙烷毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX4110000
- CHEMICAL NAME :
- Propane, 1-bromo-
- CAS REGISTRY NUMBER :
- 106-94-5
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C3-H7-Br
- MOLECULAR WEIGHT :
- 123.01
- WISWESSER LINE NOTATION :
- E3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 101,321,1982
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 253 gm/m3/30M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAVUAI Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. (Izdatel'stvo Naukova Dumka, Kiev, USSR) No.1- 1966- Volume(issue)/page/year: 7,35,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2950 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,102,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2530 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,102,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 98408 mg/m3/30M/1W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 80,139,1944 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- male 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 101,321,1982
溴代丙烷安全信息
[ 符号 ]:
GHS02, GHS07, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H225-H315-H319-H335-H336-H351-H360FD-H373-H412-H420
[ 警示性声明 ]:
P201-P210-P280-P308 + P313-P370 + P378-P403 + P235
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
F:Flammable
[ 风险声明 (欧洲) ]:
R11;R36/37/38;R48/20;R60;R63;R67
[ 安全声明 (欧洲) ]:
S53-S45
[ 危险品运输编码 ]:
UN 2344 3/PG 2
[ WGK德国 ]:
2
[ RTECS号 ]:
TX4110000
[ 包装等级 ]:
II
[ 危险类别 ]:
3
[ 海关编码 ]:
2903399090
溴代丙烷合成路线
溴代丙烷上下游产品
溴代丙烷上游产品
溴代丙烷下游产品
溴代丙烷制备
1.由正丙醇与氢溴酸反应而得。将氢溴酸加入浓硫酸中，再加入正丙醇，加热回流0.5h。于70-75℃将生成的溴丙烷全部蒸出，然后用浓盐酸洗，再用碳酸钠中和至pH为7。用无水硫酸钠干燥，过滤，滤液蒸馏，收集69-74℃馏分，得溴丙烷。
2.由正丙醇与溴化钠反应而得。将正丙醇和水、溴化钠一起加热至回流，保持69-72℃滴加硫酸，加毕，继续回流2h。蒸馏，收集68-100℃馏出液，用碳酸钠溶液洗至中性，再蒸馏，收集68-76℃馏出液即溴丙烷。另外，在红磷存在下，正丙醇与溴反应也可制备溴丙烷。
3.制法：
于反应瓶中加入48%的氢溴酸500g，水浴冷却，搅拌下慢慢加入浓硫酸150g(82mL),再加入正丙醇(2)144g（2.4mol），慢慢加热，并由滴液漏斗滴加浓硫酸65mL，同时蒸出生成的1-溴丙烷。接引管伸入接受瓶中水面下，接受瓶用冰水冷却。待无溴丙烷蒸出时，停止反应。分出馏出物中的粗溴丙烷，依次用水、5%的碳酸钠溶液、水洗涤，无水氯化钙干燥。水浴加热蒸馏，收集70～72℃的馏分，得1-溴丙烷(1)①255g,收率86%。注：①也用溴化钠、硫酸和丙醇反应来制备1-溴丙烷。
溴代丙烷海关
[ 海关编码 ]: 2903399090
[ 中文概述 ]:
2903399090. 其他无环烃的氟化、溴化或碘化衍生物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
溴代丙烷文献
J. Am. Chem. Soc. 133(41) , 16560-5, (2011)
Adsorbates on metals, but not previously on semiconductors, have been observed to display long-range repulsive interactions. On metals, due to efficient dissipation, the repulsions are weak, typically...
Apoptosis contributes to testicular toxicity induced by two isomers of bromopropanes.Toxicol. Ind. Health 26(8) , 513-24, (2010)
The aim of this study was to investigate the different testicular toxicity and the role of apoptosis in the possible mechanism induced by the two isomers of bromopropanes (BPs) in the same dosage. Fol...
Neuro-reproductive toxicities of 1-bromopropane and 2-bromopropane.Int. Arch. Occup. Environ. Health 78(2) , 79-96, (2005)
2-Bromopropane was used as an alternative to chlorofluorocarbons in a Korean electronics factory and caused reproductive and hematopoietic disorders in male and female workers. This causality was reve...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥165.0/500g
联系人：刘佳
产品详情：1-溴丙烷
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥122.0/500g
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：1-溴丙烷
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相关化合物
【溴代丙烷】化源网提供溴代丙烷CAS号106-94-5，溴代丙烷MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询溴代丙烷上化源网，专业又轻松。>>电脑版：溴代丙烷
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