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2-甲胺乙醇

2-甲胺乙醇用途

【用途一】
用作医药、有机合成中间体

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2-甲胺乙醇名称

[ CAS 号 ]:
109-83-1

[ 中文名 ]:
N-甲基-2-羟基乙胺

[ 英文名 ]:
2-Methylaminoethanol

[中文别名 ]:

[英文别名 ]:

MFCD00002839
2-Hydroxypropanamine
2-(Methylamino)ethanol
(RS)-1-Amino-2-hydroxypropane
1-Amino-2-hydroxypropane
propan-2-ol, 1-amino-
N-Methylethanolamine
2-Methylaminoethanol
(±)-1-Amino-2-propanol
1-Aminopropan-2-ol

2-甲胺乙醇物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
159.9±13.0 °C at 760 mmHg

[ 熔点 ]:
-3 °C

[ 分子式 ]:
C₃H₉NO

[ 分子量 ]:
75.110

[ 闪点 ]:
73.9±0.0 °C

[ 精确质量 ]:
75.068413

[ PSA ]:
32.26000

[ LogP ]:
-0.96

[ 外观性状 ]:
无色液体,无悬浮物

[ 蒸汽密度 ]:
2.6 (vs air)

[ 蒸汽压 ]:
0.9±0.6 mmHg at 25°C

[ 折射率 ]:
1.440

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Combustible. Incompatible with oxidizing agents.

[ 水溶解性 ]:
miscible

2-甲胺乙醇MSDS

2-甲胺乙醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL6650000

CHEMICAL NAME :: Ethanol, 2-(methylamino)-

CAS REGISTRY NUMBER :: 109-83-1

BEILSTEIN REFERENCE NO. :: 1071196

LAST UPDATED :: 199806

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C3-H9-N-O

MOLECULAR WEIGHT :: 75.13

WISWESSER LINE NOTATION :: Q2M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 1/20/1972 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2340 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1330 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 12,486,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1802 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 225,428,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1070 uL/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536158 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4016 No. of Facilities: 7733 (estimated) No. of Industries: 36 No. of Occupations: 28 No. of Employees: 39013 (estimated) No. of Female Employees: 11887 (estimated)

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2-甲胺乙醇安全信息

[ 符号 ]:

GHS05, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302 + H312-H314-H335-H373

[ 警示性声明 ]:
P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ 靶器官 ]:
Epididymus, Kidney, Liver, Testes, ovary, spleen

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R21/22;R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2735 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
KL6650000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
29221980

2-甲胺乙醇合成路线

2-甲胺乙醇上下游产品

2-甲胺乙醇上游产品

2-甲胺乙醇下游产品

2-甲胺乙醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Initial attempts to express a choline oxidase from Arthrobacter pascens (APChO-syn) in Escherichia coli starting from a synthetic gene only led to inactive protein. However, activity was regained by t...

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