正己烷

正己烷用途

【用途一】
用于溶剂、萃取、有机合成，如用于电子行业清洗，制药行业中作萃取剂，食用植物油的提取剂等
【用途二】
用于溶剂、萃取、有机合成，电子行业用于清洗，制药工业中作萃取剂，也是食用植物油的提取剂
【用途三】
用作分析试剂和溶剂
【用途四】
萃取溶剂。
【用途五】
主要用作溶剂，如植物油抽提溶剂、丙烯聚合溶剂、橡胶和涂料溶剂、颜料稀释剂。用于大豆、米糠、棉籽等各种食用油脂和香辛料中油脂等的抽提。此外，它还是高辛烷值燃料。
【用途六】
溶剂。甲醇中水分测定。紫外光谱分析。农药残留分析。高效液相色谱。气相色谱分析标准。生化研究，蛋白质顺序分析。测定矿物折光率。有机合成。温度计中代替汞。

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正己烷名称

[ CAS 号 ]:
110-54-3

[ 中文名 ]:
正己烷

[ 英文名 ]:
N-hexane

[中文别名 ]:

[英文别名 ]:

n-Hexane,AcroSeal,Extra Dry
MFCD02179311
n-Hexane,ECD tested halocarbons free grade
n-Hexane,residue free
EINECS 203-777-6
Residual Solvent Class 2 - Hexane
N-hexane

正己烷物理化学性质

[ 密度 ]:
0.7±0.1 g/cm3

[ 沸点 ]:
68.5±3.0 °C at 760 mmHg

[ 熔点 ]:
-95ºC

[ 分子式 ]:
C₆H₁₄

[ 分子量 ]:
86.175

[ 闪点 ]:
-23.3±0.0 °C

[ 精确质量 ]:
86.109550

[ LogP ]:
3.94

[ 外观性状 ]:
无色液体带有一种像汽油的气味

[ 蒸汽密度 ]:
3.5 (vs air)

[ 蒸汽压 ]:
150.9±0.1 mmHg at 25°C

[ 折射率 ]:
1.384

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 稳定性 ]:
Stable. Incompatible with oxidizing agents, chlorine, fluorine, magnesium perchlorate. Highly flammable. Readily forms explosive mixtures with air. Note low flash point.

[ 水溶解性 ]:
insoluble

正己烷MSDS

详细MSDS(安全技术说明书)

正己烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MN9275000

CHEMICAL NAME :: Hexane

CAS REGISTRY NUMBER :: 110-54-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 61

MOLECULAR FORMULA :: C6-H14

MOLECULAR WEIGHT :: 86.20

WISWESSER LINE NOTATION :: 6H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 190 ppm/8W

TOXIC EFFECTS :: Peripheral Nerve and Sensation - structural change in nerve or sheath

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28710 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 48000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 gm/m3

TOXIC EFFECTS :: Behavioral - general anesthetic Lungs, Thorax, or Respiration - respiratory depression Cardiac - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 831 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex)

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 132 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2000 ppm/12H/24W-I

TOXIC EFFECTS :: Spinal Cord - other degenerative changes Peripheral Nerve and Sensation - recording from peripheral motor nerve Biochemical - Metabolism (Intermediary) - other proteins

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 gm/kg/4W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1000 ppm/24H/11W-C

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - muscle weakness Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 pph/6H/13W-I

TOXIC EFFECTS :: Brain and Coverings - changes in brain weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 476 ppm/6H/4W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3000 ppm/6H/2Y-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ppm/24H/9W-C

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18900 mg/kg/35D-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - recording from afferent nerve Peripheral Nerve and Sensation - recording from peripheral motor nerve Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4788 mg/kg/7D-I

TOXIC EFFECTS :: Liver - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - multiple enzyme effects

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 ppm/12H/16W-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - recording from peripheral motor nerve Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - other proteins

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10000 ppm/6H/13W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - changes in motor activity (specific assay) Blood - changes in other cell count (unspecified)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 18 gm/kg/90D-I

TOXIC EFFECTS :: Peripheral Nerve and Sensation - structural change in nerve or sheath Behavioral - ataxia Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 10000 ppm/7H

SEX/DURATION :: female 15 day(s) pre-mating female 1-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1000 ppm/6H

SEX/DURATION :: female 8-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 5000 ppm/20H

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 238 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Fibroblast

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** REVIEWS *** ACGIH TLV-TWA 176 mg/m3 (50 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 500 ppm (1800 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,126,1971 OSHA PEL (Gen Indu):8H TWA 500 ppm (1800 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 500 ppm (1800 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 500 ppm (1800 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 500 ppm (1800 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 50 ppm (180 mg/m3) JAN 1993 OEL-BELGIUM:TWA 50 ppm (176 mg/m3) JAN 1993 OEL-DENMARK:TWA 50 ppm (180 mg/m3) JAN 1993 OEL-FINLAND:TWA 50 ppm (180 mg/m3);STEL 150 ppm (530 mg/m3) JAN 1993 OEL-FRANCE:TWA 50 ppm (170 mg/m3) JAN 1993 OEL-GERMANY:TWA 50 ppm (180 mg/m3) JAN 1993 OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m3;Skin JAN 1993 OEL-JAPAN:TWA 40 ppm (140 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 100 ppm (360 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 500 ppm (1800 mg/m3) JAN 1993 OEL-POLAND:TWA 400 mg/m3 JAN 1993 OEL-RUSSIA:TWA 40 ppm;STEL 300 mg/m3 JAN 1993 OEL-SWEDEN:TWA 25 ppm (90 mg/m3);STEL 50 ppm (180 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 50 ppm (180 mg/m3);STEL 100 ppm (360 mg/m3) JAN 1993 OEL-TURKEY:TWA 500 ppm (1800 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 100 ppm (360 mg/m3);STEL 125 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO HEXANE-air:10H TWA 50 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 36955 No. of Facilities: 72257 (estimated) No. of Industries: 281 No. of Occupations: 168 No. of Employees: 763261 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 36955 No. of Facilities: 40256 (estimated) No. of Industries: 221 No. of Occupations: 161 No. of Employees: 643101 (estimated) No. of Female Employees: 138726 (estimated)

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正己烷安全信息

[ 符号 ]:

GHS02, GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H304-H315-H336-H361f-H373-H411

[ 警示性声明 ]:
P201-P210-P273-P301 + P310-P308 + P313-P331

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R11;R38;R48/20;R51/53;R62;R65;R67

[ 安全声明 (欧洲) ]:
S16-S29-S33-S36/37-S61-S62-S9

[ 危险品运输编码 ]:
UN 1208

[ WGK德国 ]:
3

[ RTECS号 ]:
MN9275000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2901100000

正己烷合成路线

详细合成路线

正己烷上下游产品

正己烷上游产品

正己烷下游产品

正己烷制备

1.存在于直馏汽油、铂重整抽余油或湿性天然气中，含量1%～15%。目前，工业生产主要是从铂重整装置的抽余油（含己烷11%～13%）中分离，用精馏法除去轻重组分后，得到含正己烷60%～80%的馏分。采用双塔连续精馏，再经0501型催化剂加氢，除去苯等不饱和烃，得到合格产品。美国还采用吸附分离法制备正己烷。

2.以正己烷为原料（正己烷含量为90%～95%），经过精密精馏制得高纯正己烷。

3.主要采用抽余油分离法。将铂重整装置的抽余油 ( 含乙烷1 1%~1 3%)精馏分离,除去轻重组分后,得正己烷,纯度为6 0%~8 0%,再以6 0~1 4 0℃的馏分为原料 ( 含正己烷1 1%~1 3%) ,采用两塔连续分离,除轻、重组分后,得含正己烷为6 0%~8 0%的馏分,最后经过0 5 0 1催化剂加氢,除去苯等不饱和烃而得正己烷。

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正己烷海关

[ 海关编码 ]: 2901100000

[ 中文概述 ]:
2901100000 饱和无环烃。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:2.0%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 用作气体燃料的应报明包装容器容积, 散装货物应报明

[ Summary ]:
2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

正己烷文献

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184.

Pharmacol. Biochem. Behav. 124 , 153-9, (2014)

The biological actions of the endocannabinoids anandamide and 2-arachidonoyl glycerol (2-AG) are terminated by enzymatic hydrolysis of these lipids via fatty acid amide hydrolase (FAAH) and monoacylgl...

Effect of germinated brown rice extracts on pancreatic lipase, adipogenesis and lipolysis in 3T3-L1 adipocytes.

Lipids Health Dis. 13 , 169, (2014)

This study investigated anti-obesity effects of seven different solvent (n-hexane, toluene, dicholoromethane, ethyl acetate, absolute methanol, 80% methanol and deionized water) extracts of germinated...

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正己烷相关知识

正己烷中毒有哪些表现？正己烷中毒怎么办？

2019-07-17 22:04:46

正己烷常态下为微有异臭的液体。分子量86.17。沸点：68.74℃。几乎不溶于水，溶于醚和醇。商品正已烷常含有一定量的苯和其他烃类。正已烷虽可经呼吸道、消化道、皮肤进入机体，但职业中毒多经呼吸道和皮肤吸收。正己烷在体内分布与器官的脂肪含量有关，主要分布于脂肪含量高的器官，如脑、肾、肝、脾、睾丸等。...

正己烷

正己烷用途

正己烷名称

正己烷物理化学性质

正己烷MSDS

详细MSDS(安全技术说明书)

正己烷毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

正己烷安全信息

正己烷合成路线

详细合成路线

正己烷上下游产品

正己烷上游产品

正己烷下游产品

正己烷制备

正己烷海关

正己烷文献

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