司替霉素
司替霉素名称
[ CAS 号 ]:
11033-34-4
[ 中文名 ]:
司替霉素
[ 英文名 ]:
1,6,11(2H)-Naphthacenetrione,4-[(6-deoxy-2-O-methyl-a-L-mannopyranosyl)oxy]-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-,(2S,3S,4R)-
[英文别名 ]:
- Steffimycinum [INN-Latin]
- Steffimycine [INN-French]
- Steffisburgensimycin
- Estefimicina [INN-Spanish]
- Steffimycin
司替霉素物理化学性质
[ 密度 ]:
1.58g/cm3
[ 沸点 ]:
813.7ºC at 760mmHg
[ 分子式 ]:
C28H30O13
[ 分子量 ]:
574.53000
[ 闪点 ]:
269.3ºC
[ 精确质量 ]:
574.16900
[ PSA ]:
198.51000
[ LogP ]:
0.38340
[ 蒸汽压 ]:
5.49E-28mmHg at 25°C
[ 折射率 ]:
1.673
司替霉素毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9456000
- CHEMICAL NAME :
- 1,6,11(2H)-Naphthacenetrione, 4-((6-deoxy-2-O-methyl-alpha-L-mannopyranosyl)oxy)-3, 4-dihydro- 3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-
- CAS REGISTRY NUMBER :
- 11033-34-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C28-H30-O13
- MOLECULAR WEIGHT :
- 574.58
- WISWESSER LINE NOTATION :
- L E6 C666 BV FV MVT&&&J GQ G1 HO1 KQ OQ QO1 IO- BT6OTJ CO1 DQ EQ F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 562 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 4500 nmol/L
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 25,59,1979
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