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L-谷氨酸二乙酯盐酸盐

L-谷氨酸二乙酯盐酸盐用途

H-Glu(OEt)-OEt。HCl是谷氨酸衍生物[1]。

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L-谷氨酸二乙酯盐酸盐名称

[ CAS 号 ]:
1118-89-4

[ 中文名 ]:
L-谷氨酸二乙酯盐酸盐

[ 英文名 ]:
H-Glu(OEt)-OEt.HCl

[中文别名 ]:

谷氨酸二乙酯盐酸盐

[英文别名 ]:

Glutamic acid, diethyl ester, hydrochloride (1:1)
diethyl (2S)-2-aminopentanedioate,hydrochloride
MFCD00012509
Diethyl L-Glutamate Hydrochloride
Diethyl L-glutamate hydrochloride (1:1)
H-Glu(OEt)-OEt·HCl
Diethyl glutamate hydrochloride (1:1)
L-Glutamic Acid Diethyl Ester Hydrochloride
EINECS 214-270-4
H-Glu(OEt)-OEt.HCl

L-谷氨酸二乙酯盐酸盐生物活性

[ 描述 ]:

H-Glu(OEt)-OEt。HCl是谷氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

L-谷氨酸二乙酯盐酸盐物理化学性质

[ 密度 ]:
1.08g/cm3

[ 沸点 ]:
262ºC at 760 mmHg

[ 熔点 ]:
108-110 °C(lit.)

[ 分子式 ]:
C₉H₁₈ClNO₄

[ 分子量 ]:
239.697

[ 闪点 ]:
86.3ºC

[ 精确质量 ]:
239.092438

[ PSA ]:
78.62000

[ LogP ]:
1.72240

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0112mmHg at 25°C

[ 折射率 ]:
22.5 ° (C=3.6, EtOH)

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
水溶性：可溶

L-谷氨酸二乙酯盐酸盐MSDS

L-谷氨酸二乙酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA1252280

CHEMICAL NAME :: L-Glutamic acid, diethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 1118-89-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H17-N-O4.Cl-H

MOLECULAR WEIGHT :: 239.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,246,1991

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L-谷氨酸二乙酯盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MA1252280

[ 海关编码 ]:
2922499990

L-谷氨酸二乙酯盐酸盐合成路线

L-谷氨酸二乙酯盐酸盐上下游产品

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L-谷氨酸二乙酯盐酸盐下游产品

L-谷氨酸二乙酯盐酸盐海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-谷氨酸二乙酯盐酸盐文献

Fast-acting excitatory amino acids are involved in the enhancement of the aversiveness of the electrical stimulation of the inferior colliculus by systemic injections of muscimol.

Life Sci. 71(25) , 2961-72, (2002)

Gradual increases in the electrical stimulation of the inferior colliculus produces progressive aversive responses from vigilance, through freezing, until escape. These responses are probably mediated...

Glycine increases arterial pressure and augments NMDA-induced pressor responses in the dorsomedial and ventrolateral medulla of cats.

J. Auton. Nerv. Syst. 67(3) , 145-55, (1997)

The present study is designed to determine and characterize two neurobiological events. Firstly, we investigated whether increases of systemic arterial pressure (SAP) and sympathetic vertebral nerve a...

Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.

Biochim. Biophys. Acta 1780(6) , 881-91, (2008)

Papain polymerizes L-glutamic acid diethyl ester (Glu-di-OEt) regioselectively, resulting in the formation of poly (gamma-ethyl alpha-L-glutamic acid) with various degrees of polymerization of less th...

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