< 生产厂家价格 >

5-(6)-羧基-2',7'-二氯荧光素

5-(6)-羧基-2',7'-二氯荧光素用途

5(6)-羧基-2’,7’-二氯荧光素是MRP2囊泡转运分析的理想底物,具有良好的检测和转运特性[1]。

点击显示

5-(6)-羧基-2',7'-二氯荧光素名称

[ CAS 号 ]:
111843-78-8

[ 中文名 ]:
5(6)-羧基-2',7'-二氯荧光素

[ 英文名 ]:
5-(6)-Carboxy-2',7'-dichlorofluorescein

[英文别名 ]:

5-(6)-羧基-2',7'-二氯荧光素生物活性

[ 描述 ]:

5(6)-羧基-2’,7’-二氯荧光素是MRP2囊泡转运分析的理想底物,具有良好的检测和转运特性[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Heredi-Szabo K, et al. Characterization of 5(6)-carboxy-2,'7'-dichlorofluorescein transport by MRP2 and utilization of this substrate as a fluorescent surrogate for LTC4. J Biomol Screen. 2008 Apr;13(4):295-301.

5-(6)-羧基-2',7'-二氯荧光素物理化学性质

[ 密度 ]:
1.86g/cm3

[ 沸点 ]:
732.3ºC at 760mmHg

[ 熔点 ]:
250ºC

[ 分子式 ]:
C₂₁H₁₀Cl₂O₇

[ 分子量 ]:
445.20600

[ 闪点 ]:
396.7ºC

[ 精确质量 ]:
443.98000

[ PSA ]:
113.29000

[ LogP ]:
4.67080

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
室温，密闭，干燥

5-(6)-羧基-2',7'-二氯荧光素MSDS

详细MSDS(安全技术说明书)

5-(6)-羧基-2',7'-二氯荧光素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

5-(6)-羧基-2',7'-二氯荧光素文献

alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores.

Free Radic. Biol. Med. 37 , 1779-1789, (2004)

Mitochondrial dysfunction and oxidative stress occur in neurodegenerative diseases. Other results show that bombesin-releasable calcium stores (BRCS) from the endoplasmic reticulum (ER) are exaggerate...

Homocysteinic acid causes oxidative stress in lymphocytes by potentiating toxic effect of NMDA.

Bull. Exp. Biol. Med. 140(1) , 33-7, (2005)

Short-term incubation of lymphocytes with homocysteine or its oxidation product homocysteinic acid increased the formation of reactive oxygen species and cell necrosis (in case of homocysteinic acid)....

Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics.

Drug Metab. Dispos. 40 , 1825-33, (2012)

Transporter gene knockout rats are practically advantageous over murine models for pharmacokinetic and excretion studies, but their phenotypic characterization is lacking. At present, relevant aspects...

更多文献