正十二烷

【用途一】
用于生产十二碳二元酸、直链醇和卤代烷，用作日化产品主要原料油等
【用途二】
用作有机合成中间体、溶剂和色谱分析的标准物质。
【用途三】
十二烷（112-40-3）被用作溶剂和蒸馏驱动剂，也是柴油平均组分之一。十二烷（112-40-3）作为氧载体可提高法夫酵母发酵时的溶氧水平，促进虾青素的合成。
【用途四】
气相色谱分析标准。有机合成。

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
216.1±3.0 °C at 760 mmHg

[ 熔点 ]:
-12ºC

[ 分子式 ]:
C₁₂H₂₆

[ 分子量 ]:
170.335

[ 闪点 ]:
71.1±0.0 °C

[ 精确质量 ]:
170.203445

[ LogP ]:
7.13

[ 外观性状 ]:
无色液体带有像汽油的气味

[ 蒸汽密度 ]:
5.96 (vs air)

[ 蒸汽压 ]:
0.2±0.2 mmHg at 25°C

[ 折射率 ]:
1.422

[ 储存条件 ]:
包装完整、轻装轻卸,库房通风、远离明火、高温、与氧化剂分开存放

[ 水溶解性 ]:
<0.1 g/100 mL at 25 ºC

详细MSDS(安全技术说明书)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

JR2125000

CHEMICAL NAME :

Dodecane

CAS REGISTRY NUMBER :

112-40-3

BEILSTEIN REFERENCE NO. :

1697175

LAST UPDATED :

199710

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C12-H26

MOLECULAR WEIGHT :

170.38

WISWESSER LINE NOTATION :

12H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2672 mg/kg

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex)

REFERENCE :

APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 37,56,1975 ** TUMORIGENIC DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

11 gm/kg/22W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,70,1966 *** REVIEWS *** TOXICOLOGY REVIEW ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 78,99,1972 TOXICOLOGY REVIEW PAASAH Publication of the American Association for the Advancement of Science. (Washington, DC) No.1-94, 1934-73. Discontinued. Volume(issue)/page/year: 54,171,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83924 No. of Facilities: 12 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 12 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83924 No. of Facilities: 96 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 5451 (estimated) No. of Female Employees: 356 (estimated)

[ 符号 ]:

GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H304

[ 警示性声明 ]:
P301 + P310-P331

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R65;R66

[ 安全声明 (欧洲) ]:
S36-S60-S62

[ 危险品运输编码 ]:
NA 1993 / PGIII

[ WGK德国 ]:
3

[ RTECS号 ]:
JR2125000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
2901100000

详细合成路线

正十二烷上游产品

正十二烷下游产品

1.制法：

于装有搅拌器、温度计、回流冷凝器(装氯化钙干燥管)的干燥的反应瓶中，加入50mL六甲基磷酰胺(HMPA)，对甲苯磺酸正十二烷酯(2)6.8g（0.0201mol），氰基硼氢化钠^①5.02g(0.08mol)。搅拌下于80℃反应2h。冷后加入50mL水，用正己烷提取三次。合并有机提取液，水洗两次，无水硫酸镁干燥，减压分镏，收集79-81℃/1.86KPa的馏分,得正十二烷(1)2.5-2.65g，收率79%-81%。注：①在六甲基磷酰胺中用氰基硼氢化钠还原卤代烷和磺酸酯是一种制备烷烃的方便方法，选择性很高，分子中的其它官能团如羧基、羧酸酯基、氰基、硝基、酰胺基、羰基、环氧乙烷基等不受影响。

2.制法：

用23g(1.0mol)金属钠同82.5g(62mL,0.5mol)1-溴己烷烷(2)或99g(65.5mL,0.5mol)1-溴戊烷按上述制备正辛烷的操作方法，收集94℃/174KPa的馏分，得约37g正癸烷(1),收率87%。 ^[2]

[ 海关编码 ]: 2901100000

[ 中文概述 ]:
2901100000 饱和无环烃。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:2.0%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 用作气体燃料的应报明包装容器容积, 散装货物应报明

[ Summary ]:
2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：十二烷

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥428.0/500ml ￥138.0/100ml

联系人：刘佳

产品详情：十二烷

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥184.9/5ml ￥114.9/100ml ￥1455.9/3l ￥49.9/25ml

联系人：阿拉丁

产品详情：十二烷

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公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥54.0/25ml ￥116.0/100ml ￥426.0/500ml ￥1471.0/2500ml

联系人：夏言

产品详情：[Perfemiker]十二烷,>99.0%(GC)

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公司名：中山市迪欣化工有限公司

区域：中山市三角镇

价格：
￥50.0/150kg

联系人：陈雪萍

产品详情：正十二烷

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