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2-氨基-2-甲基-1,3-丙二醇(AMPD)

2-氨基-2-甲基-1,3-丙二醇(AMPD)用途

2-氨基-2-甲基-1,3-丙二醇是一种固-固相相变材料。氨基-2-甲基-1,3-丙二醇可用于制备表面活性剂、硫化促进剂和生物缓冲剂[1]。

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2-氨基-2-甲基-1,3-丙二醇(AMPD)名称

[ CAS 号 ]:
115-69-5

[ 中文名 ]:
2-氨基-2-甲基-1,3-丙二醇

[ 英文名 ]:
2-Amino-2-methyl-1,3-propanediol

[中文别名 ]:

[英文别名 ]:

AMPD,Ammediol
1,3-Propanediol, 2-amino-2-methyl-
2-amino-2-methylpropane-1,3-diol
2-Amino-2-methyl-1,3-propanediol
EINECS 204-100-7
MFCD00004678

2-氨基-2-甲基-1,3-丙二醇(AMPD)生物活性

[ 描述 ]:

2-氨基-2-甲基-1,3-丙二醇是一种固-固相相变材料。氨基-2-甲基-1,3-丙二醇可用于制备表面活性剂、硫化促进剂和生物缓冲剂[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. RyoheiGotoh, et al. Controlling heat release of crystallization from supercooling state of a solid-solid PCM, 2-amino-2-methyl-1,3-propanediol. International Journal of Heat and Mass Transfer, 2019, 1132-1140.

2-氨基-2-甲基-1,3-丙二醇(AMPD)物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
271.5±0.0 °C at 760 mmHg

[ 熔点 ]:
100-110 °C(lit.)

[ 分子式 ]:
C₄H₁₁NO₂

[ 分子量 ]:
105.136

[ 闪点 ]:
109.7±21.8 °C

[ 精确质量 ]:
105.078979

[ PSA ]:
66.48000

[ LogP ]:
-1.16

[ 外观性状 ]:
白色粉末

[ 蒸汽密度 ]:
3.63 (vs air)

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.494

[ 储存条件 ]:
库房通风低温干燥

[ 稳定性 ]:
Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids.

[ 水溶解性 ]:
2500 g/L (20 ºC)

2-氨基-2-甲基-1,3-丙二醇(AMPD)MSDS

2-氨基-2-甲基-1,3-丙二醇(AMPD)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY2975000

CHEMICAL NAME :: 1,3-Propanediol, 2-amino-2-methyl-

CAS REGISTRY NUMBER :: 115-69-5

BEILSTEIN REFERENCE NO. :: 0635708

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H11-N-O2

MOLECULAR WEIGHT :: 105.16

WISWESSER LINE NOTATION :: Q1XZ1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - coma

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 22,315,1940 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82132 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 66 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82132 No. of Facilities: 663 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 7513 (estimated) No. of Female Employees: 5523 (estimated)

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2-氨基-2-甲基-1,3-丙二醇(AMPD)安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H290-H315-H319-H335

[ 警示性声明 ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
UN 3259 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
TY2975000

[ 危险类别 ]:
8.0

[ 海关编码 ]:
29221980

2-氨基-2-甲基-1,3-丙二醇(AMPD)合成路线

2-氨基-2-甲基-1,3-丙二醇(AMPD)上下游产品

2-氨基-2-甲基-1,3-丙二醇(AMPD)上游产品

2-氨基-2-甲基-1,3-丙二醇(AMPD)下游产品

2-氨基-2-甲基-1,3-丙二醇(AMPD)海关

[ 海关编码 ]: 29221980

2-氨基-2-甲基-1,3-丙二醇(AMPD)文献

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Int. J. Toxicol. 28(6 Suppl) , 141S-61S, (2009)

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