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亚麻酸乙酯

亚麻酸乙酯用途

亚麻酸乙酯是一种脂肪酸乙酯(FAEE)。亚麻酸乙酯在抑制细胞产生黑色素方面发挥积极作用,IC50为70μM。抗黑素生成作用[1]。

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亚麻酸乙酯名称

[ CAS 号 ]:
1191-41-9

[ 中文名 ]:
亚麻酸乙酯

[ 英文名 ]:
Ethyl linolenate

[中文别名 ]:

[英文别名 ]:

ethyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoatato
Ethyl linolenate
LINOLENIC ACID ETHYL ESTER
EINECS 214-734-6
Ethyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
MFCD00009388
(9Z,12Z,15Z)-Ethyl octadeca-9,12,15-trienoate
Ethyl (9Z,12Z,15Z)-9,12,15-octadecatrienoate

亚麻酸乙酯生物活性

[ 描述 ]:

亚麻酸乙酯是一种脂肪酸乙酯(FAEE)。亚麻酸乙酯在抑制细胞产生黑色素方面发挥积极作用,IC50为70μM。抗黑素生成作用[1]。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> G 蛋白偶联受体/G 蛋白 >> MCHR1(GPR24)

[体外研究]

亚麻酸乙酯显著阻断Forskolin诱导的黑素生成并抑制酪氨酸酶活性[1]。

[参考文献]

[1]. Sungran Huh, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull. 2010;33(7):1242-5.

亚麻酸乙酯物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
374.4±0.0 °C at 760 mmHg

[ 分子式 ]:
C₂₀H₃₄O₂

[ 分子量 ]:
306.483

[ 闪点 ]:
100.7±20.4 °C

[ 精确质量 ]:
306.255890

[ PSA ]:
26.30000

[ LogP ]:
7.49

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.475

[ 储存条件 ]:
−20°C

亚麻酸乙酯MSDS

亚麻酸乙酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG2185000

CHEMICAL NAME :: 9,12,15-Octadecatrienoic acid, ethyl ester, (Z,Z,Z)-

CAS REGISTRY NUMBER :: 1191-41-9

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H34-O2

MOLECULAR WEIGHT :: 306.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 111250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1251,1990

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亚麻酸乙酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
RG2185000

[ 海关编码 ]:
2916190090

亚麻酸乙酯合成路线

亚麻酸乙酯上下游产品

亚麻酸乙酯上游产品

亚麻酸乙酯下游产品

亚麻酸乙酯海关

[ 海关编码 ]: 2916190090

[ 中文概述 ]:
2916190090 其他不饱和无环一元羧酸（包括其酸酐、酰卤化物，过氧化物和过氧酸以及它们的衍生物）。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

亚麻酸乙酯文献

A comparative study of biodiesel production using methanol, ethanol, and tert-butyl methyl ether (MTBE) under supercritical conditions.

Bioresour. Technol. 191 , 306-11, (2015)

In this study, biodiesel production under supercritical conditions among methanol, ethanol, and tert-butyl methyl ether (MTBE) was compared in order to elucidate the differences in their reaction beha...

In vitro effects of ethanol, acetaldehyde and fatty acid ethyl esters on human erythrocytes.

Alcohol Alcohol. 37(2) , 179-86, (2002)

In vitro experiments were performed to determine if ethanol was metabolized by human erythrocytes and to investigate if ethanol or its metabolites, acetaldehyde and fatty acid ethyl esters, affected e...

Development of a new immunoassay for the detection of ethyl glucuronide (EtG) in meconium: validation with authentic specimens analyzed using LC-MS/MS. Preliminary results.

Clin. Chem. Lab Med. 52(8) , 1179-85, (2014)

Ethyl glucuronide (EtG) measurement in neonatal meconium has emerged as a reliable marker to objectively assess prenatal exposure to maternal ethanol complementary to fatty acid ethyl ester (FAEEs) me...

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