N-苯基二乙醇胺

N-苯基二乙醇胺用途

【用途一】
用作染料中间体
【用途二】
用作医药、染料的中间体，用于生产抗肿瘤药N-甲酰溶肉瘤素、抗瘤氨酸。也用于生产染料尼龙山红玉N-5BL（Nylosan Rubine N-5BL，C.I.Acid Red 299，12220-29-0]）。此染料也称弱酸酱红5BL或弱酸红玉N-5BL，用于羊毛、锦纶的染色，并可用于皮革染色。
【用途三】
用作医药、染料的中间体，用于生产抗肿瘤药N-甲酰溶肉瘤素、抗瘤氨酸,也用于生产染料尼龙山红玉N-5BL（Nylosan Rubine N-5BL，C.I.Acid Red 299，12220-29-0]）,此染料也称弱酸酱红5BL或弱酸红玉N-5BL，用于羊毛、锦纶的染色，并可用于皮革染色,N-甲酰溶肉瘤素,抗瘤氨酸的中间体，亦是染料的中间体。

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N-苯基二乙醇胺名称

[ CAS 号 ]:
120-07-0

[ 中文名 ]:
N,N-二羟乙基苯胺

[ 英文名 ]:
2,2'-(Phenylimino)diethanol

[中文别名 ]:

[英文别名 ]:

N,N-Di(β-hydroxyethyl)aniline
N,N-Dihydroxy ethyl aniline (NNDHEA)
Ethanol, 2,2'- (phenylimino)bis-
[Bis(2-hydroxyethyl)amino]benzene
MFCD00002845
N,N-Bis(2-hydroxyethyl)aniline
EINECS 204-368-5
Ethanol, 2,2'-(phenylimino)bis-
N,N-Bis(β-hydroxyethyl)aniline
N-Phenyldiethanolamine

N-苯基二乙醇胺物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
347.8±27.0 °C at 760 mmHg

[ 熔点 ]:
56-58 °C(lit.)

[ 分子式 ]:
C₁₀H₁₅NO₂

[ 分子量 ]:
181.232

[ 闪点 ]:
189.7±22.4 °C

[ 精确质量 ]:
181.110275

[ PSA ]:
43.70000

[ LogP ]:
0.81

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽密度 ]:
>1 (vs air)

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.596

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
45 g/L (20 ºC)

N-苯基二乙醇胺MSDS

详细MSDS(安全技术说明书)

N-苯基二乙醇胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM2100000

CHEMICAL NAME :: Ethanol, 2,2'-(phenylimino)di-

CAS REGISTRY NUMBER :: 120-07-0

BEILSTEIN REFERENCE NO. :: 2096832

LAST UPDATED :: 199712

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H15-N-O2

MOLECULAR WEIGHT :: 181.26

WISWESSER LINE NOTATION :: Q2NR&2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/13/1960

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/13/1960 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 980 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 360 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(4),54,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 6/13/1960 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14400 mg/kg/30D-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(4),54,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4458 No. of Facilities: 169 (estimated) No. of Industries: 11 No. of Occupations: 12 No. of Employees: 4480 (estimated) No. of Female Employees: 2229 (estimated)

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N-苯基二乙醇胺安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R41

[ 安全声明 (欧洲) ]:
S26-S39-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
KM2100000

[ 海关编码 ]:
29221980

N-苯基二乙醇胺合成路线

详细合成路线

N-苯基二乙醇胺上下游产品

N-苯基二乙醇胺上游产品

N-苯基二乙醇胺下游产品

N-苯基二乙醇胺制备

由苯胺与环氧乙烷加成而得。

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N-苯基二乙醇胺海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-苯基二乙醇胺

N-苯基二乙醇胺用途

N-苯基二乙醇胺名称

N-苯基二乙醇胺物理化学性质

N-苯基二乙醇胺MSDS

详细MSDS(安全技术说明书)

N-苯基二乙醇胺毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

N-苯基二乙醇胺安全信息

N-苯基二乙醇胺合成路线

详细合成路线

N-苯基二乙醇胺上下游产品

N-苯基二乙醇胺上游产品

N-苯基二乙醇胺下游产品

N-苯基二乙醇胺制备

N-苯基二乙醇胺海关

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