氯非沙胺
氯非沙胺名称
[ CAS 号 ]:
1223-36-5
[ 中文名 ]:
氯非沙胺
[ 英文名 ]:
2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
[英文别名 ]:
- ANP 246
- Clofexamide
- EINECS 214-951-6
- IEM 455
- Amichlophene
- Chlofexamide
- NP 246
氯非沙胺物理化学性质
[ 密度 ]:
1.12g/cm3
[ 沸点 ]:
449.7ºC at 760 mmHg
[ 分子式 ]:
C14H21ClN2O2
[ 分子量 ]:
284.78200
[ 闪点 ]:
225.8ºC
[ 精确质量 ]:
284.12900
[ PSA ]:
41.57000
[ LogP ]:
2.56770
[ 蒸汽压 ]:
2.81E-08mmHg at 25°C
[ 折射率 ]:
1.522
[ 储存条件 ]:
库房低温,通风,干燥
氯非沙胺毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB5822500
- CHEMICAL NAME :
- Acetamide, 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl)-
- CAS REGISTRY NUMBER :
- 1223-36-5
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H21-Cl-N2-O2
- MOLECULAR WEIGHT :
- 284.82
- WISWESSER LINE NOTATION :
- GR DO1VM2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1040 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 17,935,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 1,444,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 290 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,154,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #2702M
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 167 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #2702M
氯非沙胺安全信息
[ 海关编码 ]:
2924299090
氯非沙胺合成路线
氯非沙胺海关
[ 海关编码 ]: 2924299090
[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 包装
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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