美非氯嗪

美非氯嗪名称

[ CAS 号 ]:
1243-33-0

[ 中文名 ]:
美非氯嗪

[ 英文名 ]:
Mefeclorazine

[英文别名 ]:

Mefeclorazina [INN-Spanish]
Mefeclorazinum [INN-Latin]
Mefeclorazine
SD 218-06
Mepheclorazin

美非氯嗪物理化学性质

[ 密度 ]:
1.16g/cm3

[ 沸点 ]:
490.1ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₅ClN₂O₂

[ 分子量 ]:
360.87800

[ 闪点 ]:
250.2ºC

[ 精确质量 ]:
360.16000

[ PSA ]:
24.94000

[ LogP ]:
3.72480

[ 蒸汽压 ]:
9.43E-10mmHg at 25°C

[ 折射率 ]:
1.57

美非氯嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL2803000

CHEMICAL NAME :: Piperazine, 1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl)-

CAS REGISTRY NUMBER :: 1243-33-0

BEILSTEIN REFERENCE NO. :: 0627902

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H25-Cl-N2-O2

MOLECULAR WEIGHT :: 360.92

WISWESSER LINE NOTATION :: T6N DNTJ A2R CO1 DO1& DR CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - central sympatholytic Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - bronchiolar dilation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,104,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 133,29,1961

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美非氯嗪安全信息

[ 海关编码 ]:
2933599090

美非氯嗪海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%