5(6)-羧基萘基荧光素

5(6)-羧基萘基荧光素用途

5(6)-羧基萘荧光素是一种pH依赖性荧光团。5(6)-羧基萘荧光素在碱性pH范围内具有良好的灵敏度,可用于光纤pH传感器的构建。5(6)-羧基萘荧光素可用作荧光pH指示剂(Ex/Em=593/668 nm)[1]。

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5(6)-羧基萘基荧光素名称

[ CAS 号 ]:
128724-35-6

[ 中文名 ]:
5(6)-羧基萘基荧光素

[ 英文名 ]:
5(6)-carboxynaphthofluorescein

[英文别名 ]:

5(6)-Carboxynaphthofluorescein

5(6)-羧基萘基荧光素生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

5(6)-羧基萘荧光素可用作荧光pH指示剂,它在pH值为6.6至8.6的范围内敏感,pKa值为7.6[1]。5(6)-羧基萘荧光素具有荧光性质,激发波长=593nm,发射光谱=668nm[1]。

[参考文献]

[1]. Nevolova S, et al. Development of Fluorescent Assay for Monitoring of Dehalogenase Activity. Biotechnol J. 2019 Mar;14(3):e1800144.

5(6)-羧基萘基荧光素物理化学性质

[ 分子式 ]:
C₂₉H₁₆O₇

[ 分子量 ]:
476.43300

[ 精确质量 ]:
476.09000

[ PSA ]:
125.04000

[ LogP ]:
6.02160

[ 外观性状 ]:
深蓝色结晶

[ 储存条件 ]:
2-8°C，密封，干燥，避光

5(6)-羧基萘基荧光素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

5(6)-羧基萘基荧光素文献

Colorful methods to detect ion channels and pores: intravesicular chromogenic probes that respond to pH, pM and covalent capture.

Org. Biomol. Chem. 7 , 1784-1792, (2009)

The activity of synthetic pores, ion channels, transporters and carriers is usually determined with fluorescent probes in vesicles or by conductance measurements in planar lipid bilayers. Elaborating ...

High-performance fiber-optic pH microsensors for practical physiological measurements using a dual-emission sensitive dye.

Anal. Chem. 69 , 863-867, (1997)

A fast and durable ratiometric pH microoptode that is highly accurate, precise, sensitive, reversible, and reproducible over the physiological ranges of pH, ionic strength, and temperature has been de...

Array biosensor based on enzyme kinetics monitoring by fluorescence spectroscopy: application for neurotoxins detection.

Biosens. Bioelectron. 22 , 3001-3007, (2007)

The aim of the present work is to develop an evanescence wave array biosensor exploiting the "kinetic" approach of enzymatic reaction and further detection of the reaction products via pH sensitive fl...

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