双(联吡啶)-4'-甲基-4-羰基吡啶钌-N-琥珀酰亚胺酯双六氟磷酸酯

用途

Ru(bpy)2(mcbpy-O-Su-酯)(PF6)2是一种有效的钌基染料。Ru(bpy)2(mcbpy-O-Su-酯)(PF6)2可以用作量子点(QD)荧光的有效猝灭剂和病毒抗原EV71的捕获探针。Ru(bpy)2(mcbpy-O-Su-酯)(PF2)2可以用于检测基质金属蛋白酶(MMP)[1][2][3]。

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名称

[ CAS 号 ]:
136724-73-7

[ 中文名 ]:
双(联吡啶)-4’-甲基-4-羰基吡啶钌-N-琥珀酰亚胺酯双六氟磷酸酯

[ 英文名 ]:
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2

[中文别名 ]:

[英文别名 ]:

ru(bpy)2(mcbpy-o-su-ester)(pf6)2

生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[体外研究]

Ru(bpy)2(mcbpy-O-Su-酯)(PF6)2可用作测量玻璃体内抗VEGF药物的流体动力学半径的标记[2]。

[参考文献]

[1]. Chen L, et al. Dual-color fluorescence and homogeneous immunoassay for the determination of human enterovirus 71. Anal Chem. 2011 Oct 1;83(19):7316-22.

[2]. Hirvonen LM, et al. Hydrodynamic Radii of Ranibizumab, Aflibercept and Bevacizumab Measured by Time-Resolved Phosphorescence Anisotropy. Pharm Res. 2016 Aug;33(8):2025-32.

[3]. HongfangGao, et al. Highly selective electrogenerated chemiluminescence biosensor for simultaneous detection of matrix metalloproteinase-2 and matrix metalloproteinase-7 in cell secretions. Sensors and Actuators B: Chemical, December 2017, 69-76.

物理化学性质

[ 分子式 ]:
C₃₆H₂₉N₇O₄Ru

[ 分子量 ]:
724.73000

[ 精确质量 ]:
725.13200

[ PSA ]:
141.02000

[ LogP ]:
5.89790

[ 储存条件 ]:
-20°C，充氩

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

文献

pH-Dependent Excited-State Dynamics of [Ru(bpy)(3)](2+)-Modified Amino Acids: Effects of an Amide Linkage and Remote Functional Groups.

Inorg. Chem. 38 , 2030, (1999)

The pH-dependent photophysical properties of a series of polypyridyl ruthenium-substituted amino acids were investigated by steady-state and time-resolved luminescence spectroscopy. [H(3)N-DAPA(Rub(2)...

Synthesis of redox derivatives of lysine and related peptides containing phenothiazine or tris(2,2'-bipyridine)ruthenium(II).

Int. J. Pept. Protein Res. 38 , 114, (1991)

Boc-L-Lysine derivatives and lysine-containing peptides bearing the electron donor 10H-phenothiazine (PTZ) or the redox chromophore tris(2,2'-bipyridine)ruthenium(II) dication ([Rub3]2+, where b is 2,...

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