甜蜜素
甜蜜素用途
甜蜜素名称
[ CAS 号 ]:
139-05-9
[ 中文名 ]:
环己基氨基磺酸钠
[ 英文名 ]:
Sodium cyclamate
[中文别名 ]:
[英文别名 ]:
- SodiuM N-CyclohexylsulfaMate
- MFCD00003827
- ibiosuc
- N-Cyclohexanesulfamic Acid Sodium Salt
- N-Cyclohexylsulfamic Acid Sodium Salt
- cyclamic
- Sodium cyclamate
- sucrum7
- EINECS 205-348-9
- sodium cyclohexanesulfamate
甜蜜素生物活性
甜蜜素物理化学性质
[ 密度 ]:
1.32g/cm3
[ 熔点 ]:
>300 °C(lit.)
[ 分子式 ]:
C6H12NNaO3S
[ 分子量 ]:
201.219
[ 精确质量 ]:
201.043564
[ PSA ]:
77.61000
[ LogP ]:
1.84060
[ 外观性状 ]:
白色粉末
[ 储存条件 ]:
室温
[ 水溶解性 ]:
>=10 g/100 mL at 20 ºC
甜蜜素MSDS
甜蜜素毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GV7350000
- CHEMICAL NAME :
- Cyclohexanesulfamic acid, monosodium salt
- CAS REGISTRY NUMBER :
- 139-05-9
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 40
- MOLECULAR FORMULA :
- C6-H12-N-O3-S.Na
- MOLECULAR WEIGHT :
- 201.24
- WISWESSER LINE NOTATION :
- L6TJ AMSWO &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1280 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1154 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 63 gm/kg/9W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 176 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 112 gm/kg/8W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 610 gm/kg/87W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 180 mg/kg
- SEX/DURATION :
- female 7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 420 gm/kg
- SEX/DURATION :
- multigenerations
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 168 gm/kg
- SEX/DURATION :
- multigenerations
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5 gm/kg
- SEX/DURATION :
- female 7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - other effects to embryo
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 252 mg/kg
- SEX/DURATION :
- female 1-21 day(s) after conception lactating female 21 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 500 mg/L
- REFERENCE :
- HEREAY Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 1947- Volume(issue)/page/year: 70,271,1972 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,178,1987 TOXICOLOGY REVIEW IDJOAS International Dental Journal. (A. Sijthoff, 37 Wagenstr, The Hague, Netherlands) V.1- 1950- Volume(issue)/page/year: 23,328,1973 TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,1,1976 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW WMWOA4 Wiener Medizinische Wochenschrift. (Brueder Hollinek, Gallgasse 40, A-1130 Vienna, Austria) V.1- 1851- Volume(issue)/page/year: 121,515,1971 TOXICOLOGY REVIEW BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,129,1983 TOXICOLOGY REVIEW BLFSBY Basic Life Sciences. (Plenum Pub. Corp., 223 Spring St., New York, NY 10003) V.1- 1973- Volume(issue)/page/year: 24,253,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83822 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 83 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83822 No. of Facilities: 294 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 5265 (estimated) No. of Female Employees: 4349 (estimated)
甜蜜素安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302
[ 警示性声明 ]:
P301 + P312 + P330
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R22
[ 安全声明 (欧洲) ]:
S36/37
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
[ RTECS号 ]:
GV7350000
[ 海关编码 ]:
2929901000
甜蜜素上下游产品
甜蜜素上游产品
甜蜜素下游产品
甜蜜素制备
是由氨基磺酸与环己胺（C6H11NH2）及氢氧化钠反应而成。
甜蜜素海关
[ 海关编码 ]: 2929901000
[ 中文概述 ]:
2929901000 环已基氨基磺酸钠(甜蜜素) 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单)
[ 申报要素 ]: 品名, 成分含量, 用途
[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单
[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验
[ Summary ]:
2929901000 sodium cyclohexylsulfamate
甜蜜素文献
Anal. Bioanal. Chem 407 , 4277-85, (2015)
Artificial sweeteners are food additives employed as sugar substitutes which are now considered to be emerging organic contaminants. In the present study, a method is developed for the determination o...
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥118.0/250mg
￥148.0/500g
联系人：刘佳
产品详情：甜蜜素
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥168.0/5ml
￥156.0/500g
￥68.0/100g
￥217.0/1kg
联系人：夏言
产品详情：[Perfemiker]甜蜜素,10.00mg/mL in H2O
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥64.9/100g
￥169.9/1kg
￥95.9/500g
￥133.9/250mg
联系人：阿拉丁李高志
产品详情：甜蜜素
公司名：湖北魏氏化学试剂股份有限公司
区域：武汉市洪山区
价格：
￥需询单/1kg
联系人：张栋
产品详情：环拉酸钠；甜蜜素
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相关化合物
【甜蜜素】化源网提供甜蜜素CAS号139-05-9，甜蜜素MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询甜蜜素上化源网，专业又轻松。>>电脑版：甜蜜素
标题：甜蜜素_MSDS_用途_密度_甜蜜素CAS号【139-05-9】_化源网 地址：https://m.chemsrc.com/mip/cas/139-05-9_895754.html