哌嗪(六水)
哌嗪(六水)用途
哌嗪(六水)名称
[ CAS 号 ]:
142-63-2
[ 中文名 ]:
哌嗪(六水)
[ 英文名 ]:
Piperazine Hexahydrate
[中文别名 ]:
[英文别名 ]:
- Diethylenediamine Hexahydrate
- piperazine,hexahydrate
- Piperazine hydrate
- Piperazine hexahydrate
- EINECS 203-808-3
- MFCD00149389
哌嗪(六水)物理化学性质
[ 密度 ]:
1.92g/cm3
[ 沸点 ]:
145-156 °C(lit.)
[ 熔点 ]:
42-44 °C(lit.)
[ 分子式 ]:
C4H22N2O6
[ 分子量 ]:
194.22700
[ 闪点 ]:
190 °F
[ 精确质量 ]:
194.14800
[ PSA ]:
79.44000
[ 外观性状 ]:
无色固体
[ 蒸汽压 ]:
4.05mmHg at 25°C
[ 储存条件 ]:
室温
[ 水溶解性 ]:
水溶性:可溶;可溶于:醇;极微溶:乙醚
哌嗪(六水)MSDS
哌嗪(六水)毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM0850000
- CHEMICAL NAME :
- Piperazine, hexahydrate
- CAS REGISTRY NUMBER :
- 142-63-2
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C4-H10-N2.6H2-O
- MOLECULAR WEIGHT :
- 194.28
- WISWESSER LINE NOTATION :
- T6N DNTJ &QH 6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,336,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84706 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84706 No. of Facilities: 9 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 127 (estimated) No. of Female Employees: 45 (estimated)
哌嗪(六水)安全信息
[ 符号 ]:
GHS05, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H314-H317-H334-H361fd
[ 警示性声明 ]:
P260-P280-P284-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ 危害码 (欧洲) ]:
C:Corrosive;
[ 风险声明 (欧洲) ]:
R34;R42/43;R52/53
[ 安全声明 (欧洲) ]:
S22-S26-S36/37/39-S45-S61
[ 危险品运输编码 ]:
UN 2579 8/PG 3
[ WGK德国 ]:
1
[ RTECS号 ]:
TM0850000
[ 包装等级 ]:
III
[ 危险类别 ]:
8
[ 海关编码 ]:
2933599090
哌嗪(六水)上下游产品
哌嗪(六水)上游产品
哌嗪(六水)下游产品
哌嗪(六水)制备
由氯乙醇经氨化、环合成哌嗪盐酸盐,再用氢氧化钠中和制得六水哌嗪,其反应式如下:
哌嗪(六水)海关
[ 海关编码 ]: 2933599090
[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
哌嗪(六水)文献
ChemSusChem 5(9) , 1724-31, (2012)
This experimental study describes efficient CO₂ capture by 2-amino-2-methyl-1-propanol (AMP)/piperazine (PZ) in ethylene glycol monoethyl ether (EGMEE, 2-ethoxyethanol) containing approximately 15 wt ...
Synthesis and anti-inflammatory effects of new piperazine and ethanolamine derivatives of H(1)-antihistaminic drugs.Mini Rev. Med. Chem. 12(12) , 1282-92, (2012)
In addition to their antihistamine effects, H1-receptor antagonists possess pharmacological properties that are not uniformly distributed among this class of drugs, such as anti-inflammatory, anti-all...
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.J. Med. Chem. 56(6) , 2311-22, (2013)
On the basis of an initial molecular modeling study suggesting the favorable binding of the "privileged" fragment 8-hydroxyquinoline with HIV-1 integrase (IN) at the IN-lens epithelium-derived growth ...
相关化工产品/化学物质:
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公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:哌嗪,六水合物
公司名:南通润丰石油化工有限公司
区域:南通市崇川区
价格:
¥需询单/1kg
¥需询单/1ton
联系人:曹经理
产品详情:六水哌嗪
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥108.0/500g
联系人:刘佳
产品详情:哌嗪,六水合物
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥44.0/100g
¥125.0/500g
¥455.0/2500g
联系人:夏言
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥693.0/250mg
¥需询单/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:哌嗪(六水)
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相关化合物
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