Neuropeptide Y (3-36) (human, rat)

Neuropeptide Y (3-36) (human, rat)用途

Neuropeptide Y (3-36) (human, rat) 是由二肽基肽酶4 (DPP4) 形成的神经肽Y (NPY) 代谢产物,是一种选择性 Y2 受体激动剂。Neuropeptide Y (3-36) (human, rat) 是由二肽基肽酶 4 (DPP4) 形成的 NPY 代谢产物。Neuropeptide Y (3-36) (human, rat) 通过 Y2 受体减少去甲肾上腺素的释放。

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Neuropeptide Y (3-36) (human, rat)名称

[ CAS 号 ]:
150138-78-6

[ 英文名 ]:
Neuropeptide Y (3-36) (human, rat)

[英文别名 ]:

NEUROPEPTIDE Y (3-36) (HUMAN, RAT)

Neuropeptide Y (3-36) (human, rat)生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 代谢疾病

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 神经肽Y受体

[参考文献]

[1]. Hubers SA, et al. DPP (Dipeptidyl Peptidase)-4 Inhibition Potentiates the Vasoconstrictor Response to NPY (Neuropeptide Y) in Humans During Renin-Angiotensin-Aldosterone System Inhibition. Hypertension. 2018;72(3):712-719.

[2]. Grandt D, et al. Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul Pept. 1996;67(1):33-37.

Neuropeptide Y (3-36) (human, rat)物理化学性质

[ 分子式 ]:
C₁₇₅H₂₆₉N₅₃O₅₄S₁

[ 分子量 ]:
4011.4

[ 储存条件 ]:
−20°C

Neuropeptide Y (3-36) (human, rat)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

Neuropeptide Y (3-36) (human, rat)文献

Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV.

Regul. Pept. 49 , 133-144, (1993)

Neuropeptide Y, peptide YY and pancreatic polypeptide share an evolutionary conserved proline-rich N-terminal sequence, a structure generally known to be inert to the attack of common proteinases, but...

Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors.

Regul. Pept. 67 , 33, (1996)

Neuropeptide Y (NPY 1-36) binds to Y1 and Y2 receptors with similar affinity. No endogenous molecular form of NPY with selectivity for Y1 or Y2 receptors has been described so far. We report the prese...

Inhibitory effects of NPY on ganglionic transmission in myenteric neurones of the guinea-pig descending colon.

Neurogastroenterol. Motil. 12 , 33-41, (2000)

Intracellular recordings were made from myenteric neurones of the guinea-pig descending colon. Neuropeptide Y (NPY) and related pancreatic polypeptides were applied by superfusion and the effects upon...

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