米托肼

米托肼名称

[ CAS 号 ]:
1508-45-8

[ 中文名 ]:
米托肼

[ 英文名 ]:
Naphtho[2,3-d]-1,3-dioxole-6-carboxylicacid,5,6,7,8-tetrahydro-8-hydroxy-7-(hydroxymethyl)-5-(3,4,5-trimethoxyphenyl)-,2-ethylhydrazide, (5R,6R,7R,8R)-

[英文别名 ]:

米托肼物理化学性质

[ 密度 ]:
1.301g/cm3

[ 沸点 ]:
619.6ºC at 760mmHg

[ 分子式 ]:
C24H30N2O8

[ 分子量 ]:
474.50400

[ 闪点 ]:
328.5ºC

[ 精确质量 ]:
474.20000

[ PSA ]:
127.74000

[ LogP ]:
2.26720

[ 蒸汽压 ]:
3.26E-16mmHg at 25°C

[ 折射率 ]:
1.587

米托肼毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TP8800000
CHEMICAL NAME :
Podophyllic acid, 2-ethylhydrazide
CAS REGISTRY NUMBER :
1508-45-8
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C24-H30-N2-O8
MOLECULAR WEIGHT :
474.56
WISWESSER LINE NOTATION :
T C566 DO FO EH&&TJ JQ K1Q LVMM2 MR CO1 DO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,1467,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 20,363,1970
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