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鸟苷2′,3′-环单磷酸钠盐

鸟苷2′,3′-环单磷酸钠盐用途

2',3'-cGMP钠是一种cGMP类似物,是二糖酶催化RNA裂解的中间体[1]。

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鸟苷2′,3′-环单磷酸钠盐名称

[ CAS 号 ]:
15718-49-7

[ 中文名 ]:
鸟苷2′,3′-环单磷酸钠盐

[ 英文名 ]:
2',3'-cGMP sodium

[英文别名 ]:

2':3'-Cycloguanosinphosphat
cyclic 2',3'-(hydrogen phosphate),monosodium salt
guanosine 2':3'-cyclic monophosphate*sodium
guanosine 2',3'-cyclophosphate monosodium salt
Natriumsalz
Guanosine 2',3'-phosphatesodium salt
guanosine 2',3'-cyclic monophosphate sodium salt

鸟苷2′,3′-环单磷酸钠盐生物活性

[ 描述 ]:

2',3'-cGMP钠是一种cGMP类似物,是二糖酶催化RNA裂解的中间体[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

2',3'-cGMP钠(10nM-100μM,120分钟)减少了[3H]3',5'-cGMP从人红细胞向内外囊泡的主动转运[2]。2',3'-cGMP钠(2μM)增加ATP酶活性[2]。

鸟苷2′,3′-环单磷酸钠盐物理化学性质

[ 密度 ]:
2.64g/cm3

[ 沸点 ]:
778.4ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₁N₅NaO₇P

[ 分子量 ]:
367.18700

[ 闪点 ]:
424.5ºC

[ 精确质量 ]:
367.02900

[ PSA ]:
187.45000

[ 蒸汽压 ]:
1.67E-25mmHg at 25°C

[ 折射率 ]:
2.064

鸟苷2′,3′-环单磷酸钠盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

鸟苷2′,3′-环单磷酸钠盐文献

Cyclic di-GMP signalling in the virulence and environmental adaptation of Xanthomonas campestris.

Mol. Microbiol. 63(2) , 429-42, (2007)

Cyclic di-GMP is a second messenger with a role in regulation of a range of cellular functions in diverse bacteria including the virulence of pathogens. Cellular levels of cyclic di-GMP are controlled...

Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA.

Structure 8(5) , 527-40, (2000)

Bacterial signal recognition particle (SRP), consisting of 4.5S RNA and Ffh protein, plays an essential role in targeting signal-peptide-containing proteins to the secretory apparatus in the cell memb...

BdlA, a chemotaxis regulator essential for biofilm dispersion in Pseudomonas aeruginosa.

J. Bacteriol. 188(21) , 7335-43, (2006)

Multiple environmental cues have been shown to trigger biofilm detachment, the transition from surface-attached, highly organized communities known as biofilms to the motile lifestyle. The goal of thi...

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