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2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D名称

[ CAS 号 ]:
162049-83-4

[ 英文名 ]:
2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D

[英文别名 ]:

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D物理化学性质

[ 分子式 ]:
C₂₀H₂₀F₃N₃O₈

[ 分子量 ]:
487.38300

[ 精确质量 ]:
487.12000

[ PSA ]:
203.90000

[ LogP ]:
2.72060

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE DMSDS

详细MSDS(安全技术说明书)

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T: Toxic;

[ 风险声明 (欧洲) ]:
R25

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

2-((3-TRIFLUOROMETHYL)PHENYL)HISTAMINE D文献

Synthesis and histamine H1 receptor agonist activity of a series of 2-phenylhistamines, 2-heteroarylhistamines, and analogues.

J. Med. Chem. 38 , 1287-1294, (1995)

New histamine derivatives characterized by a (substituted) aryl, heteroaryl, benzyl, or heteroarylmethyl substituent in the C2 position of the imidazole ring have been prepared from appropriate imidat...

Role of histamine and its receptor subtypes in stimulation of conjunctival goblet cell secretion.

Invest. Ophthalmol. Vis. Sci. 53(6) , 2993-3003, (2012)

The purpose of this study was to determine the effect of histamine and its receptors on goblet cell secretion.Cultured rat and human goblet cells were grown in RPMI 1640. Goblet cell secretion of high...

Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.

J. Pharmacol. Exp. Ther. 305 , 1104-1115, (2003)

Species isoforms of histamine H2-, H3-, and H4-receptors differ in their pharmacological properties. The study aim was to dissect differences between the human H1R (hH1R) and guinea pig H1R (ghH1R). W...

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