3-(二甲基氨基)丙腈
3-(二甲基氨基)丙腈用途
用于固氮酶细胞分析中蛋白质、酶、核酸分子量的圆盘电泳法的测定
【用途二】
β-二甲氨基丙腈是杀菌剂霜霉威的中间体。
【用途三】
有机合成中间体，用于合成多种维生素B，也可用作有机溶剂、高分子合成引发剂（促聚剂）以及电镀添加剂的中间体。作为分析试剂，用于固氮酶细胞的分析中蛋白质、酶、核梅分子量的圆盘电泳法的测定。
3-(二甲基氨基)丙腈名称
[ CAS 号 ]:
1738-25-6
[ 中文名 ]:
二甲氨基丙腈
[ 英文名 ]:
Dimethylaminopropionitrile
[中文别名 ]:
[英文别名 ]:
- 2-DIMETHYLAMINOETHYL CYANIDE
- Cyanogum41catalyst
- MFCD00001957
- 3-(Dimethylamino)propanenitrile
- 3-(DIMETHYLAMINO)PROPIONITRILE
- EINECS 217-090-4
- Dimethylaminopropion
- 3-(N,N-dimethylamino)-propionitrile
- 3-dimethylaminopropannitril
- 3-(dimethylamino)-propionitril
3-(二甲基氨基)丙腈物理化学性质
[ 密度 ]:
0.87 g/mL at 25 °C(lit.)
[ 沸点 ]:
171 °C750 mm Hg(lit.)
[ 熔点 ]:
−43 °C(lit.)
[ 分子式 ]:
C5H10N2
[ 分子量 ]:
98.14630
[ 闪点 ]:
145 °F
[ 精确质量 ]:
98.08440
[ PSA ]:
27.03000
[ LogP ]:
0.46168
[ 外观性状 ]:
无色,非固定的流体
[ 蒸汽压 ]:
1.24mmHg at 25°C
[ 折射率 ]:
n20/D 1.426(lit.)
[ 储存条件 ]:
库房通风低温干燥,与食品、氧化剂、酸类分开储运
[ 水溶解性 ]:
0.5 g/L (20 ºC)
3-(二甲基氨基)丙腈MSDS
3-(二甲基氨基)丙腈毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UG1575000
- CHEMICAL NAME :
- Propionitrile, 3-(dimethylamino)-
- CAS REGISTRY NUMBER :
- 1738-25-6
- BEILSTEIN REFERENCE NO. :
- 0773779
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C5-H10-N2
- MOLECULAR WEIGHT :
- 98.17
- WISWESSER LINE NOTATION :
- NC2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2600 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,923,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00201
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1410 uL/kg
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DIMETHYLAMINOPROPIONITRILE-air:min expos to NIAX REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3293 No. of Facilities: 145 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1990 (estimated)
3-(二甲基氨基)丙腈安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302 + H312-H319
[ 警示性声明 ]:
P280-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
R21;R36/38
[ 安全声明 (欧洲) ]:
S26-S36/37-S24/25
[ 危险品运输编码 ]:
2927
[ WGK德国 ]:
1
[ RTECS号 ]:
UG1575000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1(a)
[ 海关编码 ]:
29269095
3-(二甲基氨基)丙腈合成路线
3-(二甲基氨基)丙腈上下游产品
3-(二甲基氨基)丙腈上游产品
3-(二甲基氨基)丙腈下游产品
3-(二甲基氨基)丙腈制备
由丙烯腈与二甲胺反应而得。先将丙烯腈在冰冷却下加入二甲胺溶液中，然后进行加热，通过吸收，分馏精馏，收集171-173℃馏分，即得本品。原料消耗定额：丙烯腈670kg/t、二甲胺（40%）1500kg/t。其制备方法是在反应釜中投入丙烯腈，开动搅拌和夹套水，在适宜的温度下通入二甲胺气体至规定量，反应1h取样分析得产品。反应方程式：
3-(二甲基氨基)丙腈海关
[ 海关编码 ]: 2926909090
[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
3-(二甲基氨基)丙腈文献
Toxicol. Appl. Pharmacol. 110(1) , 61-9, (1991)
The urotoxicity and metabolism of N,N'-dimethylaminopropionitrile (DMAPN) were investigated in male Sprague-Dawley rats. Animals treated with 525 mg DMAPN/kg or equimolar doses of commercially availab...
Purification of RNA molecules by gel techniques.Meth. Enzymol. 180 , 14-25, (1989)
[Morbidity study of employees exposed to dimethylaminopropionitrile].
Zentralbl. Arbeitsmed. Arbeitsschutz. Prophyl. Ergonomie 32(5) , 181-4, (1982)
相关化工产品/化学物质：
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥338.0/100ml
￥108.0/25ml
联系人：刘佳
产品详情：3-(二甲基氨基)丙腈
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
￥需询单/1g
联系人：阿拉丁李高志
产品详情：二甲胺基丙腈
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相关化合物
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