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二苯基乙酰氯

二苯基乙酰氯名称

[ CAS 号 ]:
1871-76-7

[ 中文名 ]:
二苯基乙酰氯

[ 英文名 ]:
Diphenylacetyl chloride

[中文别名 ]:

二苯乙酰氯

[英文别名 ]:

2,2-di(phenyl)acetyl chloride
2,2-di(phenyl)ethanoyl chloride
Diphenylacetyl chloride
Diphenylacetic acid chloride
EINECS 217-493-5
2,2-diphenylacetyl chloride
α,α-Diphenylacetyl chloride
Acetyl chloride,diphenyl
1,1-diphenylacetyl chloride
MFCD00013655

二苯基乙酰氯物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
304.9±0.0 °C at 760 mmHg

[ 熔点 ]:
49-53 °C(lit.)

[ 分子式 ]:
C₁₄H₁₁ClO

[ 分子量 ]:
230.689

[ 闪点 ]:
154.9±18.0 °C

[ 精确质量 ]:
230.049850

[ PSA ]:
17.07000

[ LogP ]:
3.96

[ 外观性状 ]:
略黄色结晶粉末

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.584

[ 储存条件 ]:
室温，密封，干燥

二苯基乙酰氯MSDS

二苯基乙酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AO6750000

CHEMICAL NAME :: Acetyl chloride, diphenyl-

CAS REGISTRY NUMBER :: 1871-76-7

BEILSTEIN REFERENCE NO. :: 1211588

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H11-Cl-O

MOLECULAR WEIGHT :: 230.70

WISWESSER LINE NOTATION :: GVYR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6330 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - ataxia

REFERENCE :: GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4700 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - ataxia

REFERENCE :: GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37980 mg/kg/26W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death

REFERENCE :: GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 17,48,1978

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二苯基乙酰氯安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34;R36/37

[ 安全声明 (欧洲) ]:
S26-S27-S28-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
AO6750000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29163900

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二苯基乙酰氯上游产品

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二苯基乙酰氯海关

[ 海关编码 ]: 29163900

二苯基乙酰氯文献

Selective pivaloylation and diphenylacetylation of cyclomalto-oligosaccharides.

Carbohydr. Res. 262(2) , 271-82, (1994)

Regioselective acylation of cyclomalto-oligosaccharides was achieved using pivaloyl and diphenylacetyl chlorides. The reaction of cyclomaltohexaose (1) with pivaloyl chloride gave the hexakis(2,6-di-O...

Synthesis and pharmacological screening of certain N-substituted amides structurally related to some local anesthetics.

Pharmazie 34(1) , 12-3, (1979)

Diphenylacetyl chloride and pivaloyl chloride have been condensed with a wide variety of amines. Some of the resulting amides showed local anesthetic properties higher than those of procaine hydrochlo...

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