< 生产厂家价格 >

去甲塞利吉林

去甲塞利吉林用途

Nordeprenyl是Deprenyl的代谢产物。Deprenyl是MAO-B的强效、选择性和不可逆抑制剂[1]。

点击显示

去甲塞利吉林名称

[ CAS 号 ]:
18913-84-3

[ 中文名 ]:
去甲塞利吉林

[ 英文名 ]:
Desmethylselegiline

[英文别名 ]:

EINECS 200-659-6

去甲塞利吉林生物活性

[ 描述 ]:

Nordeprenyl是Deprenyl的代谢产物。Deprenyl是MAO-B的强效、选择性和不可逆抑制剂[1]。

[ 相关类别 ]:

研究领域 >> 代谢疾病

[参考文献]

[1]. Yoshida T, et, al. Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency. Xenobiotica. 1986 Feb;16(2):129-36.

去甲塞利吉林物理化学性质

[ 分子式 ]:
C₁₂H₁₅N

[ 分子量 ]:
173.25

[ 闪点 ]:
9℃

[ 储存条件 ]:
-20°C Freezer, Under Inert Atmosphere

去甲塞利吉林安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301 + H311 + H331-H370

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25

[ 安全声明 (欧洲) ]:
7-16-36/37-45

[ 危险品运输编码 ]:
UN1230 - class 3 - PG 2 - Methanol, solution

去甲塞利吉林文献

Simultaneous determination of selegiline and desmethylselegiline in human body fluids by headspace solid-phase microextraction and gas chromatography-mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 844(2) , 283-91, (2006)

A method for the simultaneous determination of selegiline and its metabolite, desmethylselegiline, in human whole blood and urine is presented. The method, which combines a fiber-based headspace solid...

Modulation of neuroendocrine--immune signaling by L-deprenyl and L-desmethyldeprenyl in aging and mammary cancer.

Mech. Ageing Dev. 123(8) , 1065-79, (2002)

The aging process is characterized by a decline in cellular functions of diverse systems of the body, including the neuroendocrine-immune network. One neuroendocrinological theory of aging is based on...

Pharmacokinetic studies of (-)-deprenyl and some of its metabolites in mouse.

J. Neural Transm. Suppl. (72) , 165-73, (2007)

(-)-Deprenyl is a selective irreversible inhibitor of MAO-B. The parent compound is responsible for the enzyme inhibitory effect, but its metabolites are also playing a role in the complex pharmacolog...

更多文献