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Mca-DEVDAPK(Dnp)-OH

Mca-DEVDAPK(Dnp)-OH用途

Mca-DEVDAP-K(Dnp)-OH是半胱氨酸天冬氨酸蛋白酶-3的荧光底物[1]。

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Mca-DEVDAPK(Dnp)-OH名称

[ CAS 号 ]:
189696-20-6

[ 中文名 ]:
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS: DNP[MCA-DEVDAP-K: DNP]

[ 英文名 ]:
Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

[英文别名 ]:

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

Mca-DEVDAPK(Dnp)-OH生物活性

[ 描述 ]:

Mca-DEVDAP-K(Dnp)-OH是半胱氨酸天冬氨酸蛋白酶-3的荧光底物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 细胞凋亡 >> 胱天蛋白酶

[ 靶点 ]

Caspase-3

[参考文献]

[1]. Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1

Mca-DEVDAPK(Dnp)-OH物理化学性质

[ 分子式 ]:
C₅₀H₆₂N₁₀O₂₂

[ 分子量 ]:
1155.08000

[ 精确质量 ]:
1154.40000

[ PSA ]:
487.22000

[ LogP ]:
3.32010

[ 储存条件 ]:
-20°C，密闭，干燥

Mca-DEVDAPK(Dnp)-OHMSDS

详细MSDS(安全技术说明书)

Mca-DEVDAPK(Dnp)-OH安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Mca-DEVDAPK(Dnp)-OH文献

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis.

Nature 380 , 723, (1996)

Binding of Fas ligand or an agonistic anti-Fas antibody induces apoptosis in Fas-bearing cells. The interleukin-1Beta-converting enzyme (ICE) is a cysteine protease that is involved in apoptosis induc...

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