五聚赖氨酸

Pentalysine is a peptide.

[ 分子式 ]:
C₃₀H₆₂N₁₀O₆

[ 分子量 ]:
658.87700

[ 精确质量 ]:
658.48500

[ PSA ]:
309.82000

[ LogP ]:
3.74790

[ 外观性状 ]:
固体

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
20°C

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia.

J. Pharmacol. Exp. Ther. 352(3) , 579-89, (2015)

Polo-like kinase 1 (Plk1), a member of the Polo-like kinase family of serine/threonine kinases, is a key regulator of multiple steps in mitosis. Here we report on the pharmacological profile of volase...

Early life stress in fathers improves behavioural flexibility in their offspring.

Nat. Commun. 5 , 5466, (2014)

Traumatic experiences in childhood can alter behavioural responses and increase the risk for psychopathologies across life, not only in the exposed individuals but also in their progeny. In some condi...

Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart.

J. Mol. Cell. Cardiol. 82 , 116-24, (2015)

Dichloroacetate (DCA) promotes pyruvate entry into the Krebs cycle by inhibiting pyruvate dehydrogenase (PDH) kinase and thereby maintaining PDH in the active dephosphorylated state. DCA has recently ...

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