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((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸名称

[ CAS 号 ]:
19542-51-9

[ 中文名 ]:
Z-Val-苯丙氨酸

[ 英文名 ]:
Z-Val-Phe-OH

[英文别名 ]:

N-Cbz-L-Val-L-Phe
Z-L-VALYL-L-PHENYLALANINE
N-CBZ-VAL-PHE
z-val-phe
N-carbobenzyloxy-Val-Phe
Cbz-Val-Phe-OH
N-BENZYLOXYCARBONYL-L-VALYL-L-PHENYLALANINE

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸物理化学性质

[ 密度 ]:
1.211 g/cm3

[ 沸点 ]:
648.6ºC at 760 mmHg

[ 分子式 ]:
C₂₂H₂₆N₂O₅

[ 分子量 ]:
398.45200

[ 闪点 ]:
346.1ºC

[ 精确质量 ]:
398.18400

[ PSA ]:
104.73000

[ LogP ]:
3.53130

[ 外观性状 ]:
白色至灰白色固体

[ 蒸汽压 ]:
1.04E-17mmHg at 25°C

[ 折射率 ]:
1.569

[ 储存条件 ]:
室温，密封，干燥

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸合成路线

详细合成路线

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸上下游产品

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸上游产品

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸下游产品

((苄氧基)羰基)-L-缬氨酰-L-苯丙氨酸文献

Inhibition of calpain is a component of nitric oxide-induced down-regulation of human mast cell adhesion.

J. Immunol. 170(1) , 287-93, (2003)

Nitric oxide is an important messenger that regulates mast cell activity by modifications to gene expression and intracellular pathways associated with exocytosis and adhesion. Integrin interactions w...

Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis.

Gastroenterology 116(1) , 168-78, (1999)

Calpain proteases have been implicated in cell death by necrosis and more recently by apoptosis. Experiments were designed to determine the role of calpain proteases in ischemic rat liver injury by me...

Calpain inhibition prevents sinusoidal endothelial cell apoptosis in the cold ischemic rat liver.

Transplantation 68(1) , 136-40, (1999)

Cold preservation of the liver followed by reperfusion results in sinusoidal endothelial cell (SEC) apoptosis. Calpain-like activity is dramatically increased during reperfusion and inhibition of calp...

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