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2,3-二氯喹喔啉

2,3-二氯喹喔啉名称

[ CAS 号 ]:
2213-63-0

[ 中文名 ]:
2,3-二氯喹喔啉

[ 英文名 ]:
2,3-Dichloroquinoxaline

[中文别名 ]:

2,3-二氯苯并哒嗪

[英文别名 ]:

2,3-Dichloroquinoxaline
2,3-DICHLORO-QUINOXALINE
2,3,6-TRIFLUOROBENZOICACID
2,3-dichloroquinoxazoline
2,3-dichloroquinaxoline
Quinoxaline,2,3-dichloro
Quinoxaline, 2,3-dichloro-
EINECS 218-667-3
MFCD00006720
2,3-dichloro quinoxaline

2,3-二氯喹喔啉物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
269.7±35.0 °C at 760 mmHg

[ 熔点 ]:
152-154 °C(lit.)

[ 分子式 ]:
C₈H₄Cl₂N₂

[ 分子量 ]:
199.037

[ 闪点 ]:
142.9±11.5 °C

[ 精确质量 ]:
197.975159

[ PSA ]:
25.78000

[ LogP ]:
3.04

[ 外观性状 ]:
灰色固体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.671

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

2,3-二氯喹喔啉MSDS

详细MSDS(安全技术说明书)

2,3-二氯喹喔啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD1720000

CHEMICAL NAME :: Quinoxaline, 2,3-dichloro-

CAS REGISTRY NUMBER :: 2213-63-0

BEILSTEIN REFERENCE NO. :: 0126076

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H4-Cl2-N2

MOLECULAR WEIGHT :: 199.04

WISWESSER LINE NOTATION :: T66 BN ENJ CG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Gastrointestinal - peritonitis Kidney, Ureter, Bladder - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534573

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03256

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2,3-二氯喹喔啉安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H319-H335

[ 警示性声明 ]:
P261-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;

[ 风险声明 (欧洲) ]:
R25;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S37/39-S28A

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ RTECS号 ]:
VD1720000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

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2,3-二氯喹喔啉文献

Synthesis of some new pyrimido[2',1':2,3]thiazolo[4,5-b]quinoxaline derivatives as anti-inflammatory and analgesic agents.

Eur. J. Med. Chem. 45 , 1976-81, (2010)

Treatment of 6-aminothiouracil (1) with 2,3-dichloroquinoxaline (2) in ethanol/TEA afforded 6-amino-2-(3-chloroquinoxalin-2-ylthio)pyrimidin-4(3H)-one (3), which was refluxed in DMF to give 2-aminopyr...

Synthesis, structure elucidation and antibacterial evaluation of new steroidal -5-en-7-thiazoloquinoxaline derivatives.

Eur. J. Med. Chem. 43 , 2257-61, (2008)

Some heterocyclic systems namely cholest-5-en-7-thiazolo[4,5-b]quinoxaline-2-yl-hydrazone] were synthesized by the reaction of cholest-5-en-7-one-thiosemicarbazone with 2,3-dichloroquinoxaline at 80 d...

AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents.

Bioorg. Med. Chem. 20(5) , 1711-22, (2012)

A direct and single-step method has been developed for the synthesis of mono and 2,3-disubstituted quinoxalines by using a AlCl(3) induced (hetero)arylation of 2,3-dichloroquinoxaline. Both symmetrica...

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