右旋溴苯那敏马来酸盐
右旋溴苯那敏马来酸盐名称
[ CAS 号 ]:
2391-03-9
[ 中文名 ]:
右旋溴苯那敏马来酸盐
[ 英文名 ]:
Dexbrompheniramine Maleate
[英文别名 ]:
- Dexbrompheniramine maleate salt
- (+)-Brompheniramine maleate salt
- (S)-Brompheniramine Maleate
右旋溴苯那敏马来酸盐物理化学性质
[ 沸点 ]:
403ºC at 760mmHg
[ 分子式 ]:
C20H23BrN2O4
[ 分子量 ]:
435.31200
[ 闪点 ]:
197.5ºC
[ 精确质量 ]:
434.08400
[ PSA ]:
90.73000
[ LogP ]:
3.63950
[ 蒸汽压 ]:
1.05E-06mmHg at 25°C
右旋溴苯那敏马来酸盐MSDS
右旋溴苯那敏马来酸盐毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US4026200
- CAS REGISTRY NUMBER :
- 2391-03-9
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C16-H19-Br-N2.C4-H4-O4
- MOLECULAR WEIGHT :
- 435.36
- WISWESSER LINE NOTATION :
- T6NJ BYR DE&2N1&1 &QV1U1VQ -+
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 191 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 104 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 176 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 106 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 259 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 3,120,1961
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右旋溴苯那敏马来酸盐安全信息
[ 危害码 (欧洲) ]:
T: Toxic;
[ 风险声明 (欧洲) ]:
25
[ 危险品运输编码 ]:
UN 2811 6.1/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
US4026200
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