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S-辛基谷胱甘肽

S-辛基谷胱甘肽用途

S-辛基谷胱甘肽是一种竞争性谷胱甘肽S-转移酶(GST)抑制剂[1]。

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S-辛基谷胱甘肽名称

[ CAS 号 ]:
24435-27-6

[ 中文名 ]:
S-辛基谷胱甘肽

[ 英文名 ]:
S-Octylglutathione

[英文别名 ]:

S-辛基谷胱甘肽生物活性

[ 描述 ]:

S-辛基谷胱甘肽是一种竞争性谷胱甘肽S-转移酶(GST)抑制剂[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

S-辛基谷胱甘肽物理化学性质

[ 分子式 ]:
C₁₈H₃₃N₃O₆S

[ 分子量 ]:
419.53600

[ 精确质量 ]:
419.20900

[ PSA ]:
184.12000

[ LogP ]:
2.43990

S-辛基谷胱甘肽安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

S-辛基谷胱甘肽文献

Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.

Biochemistry 44 , 1174-1183, (2005)

Glutathione S-transferases are a family of multifunctional enzymes involved in the metabolism of drugs and xenobiotics. Two tyrosine residues, Tyr 7 and Tyr 111, in the active site of the enzyme play ...

An XAS investigation of product and inhibitor complexes of Ni-containing GlxI from Escherichia coli: mechanistic implications.

Biochemistry 40(15) , 4569-82, (2001)

Escherichia coli glyoxalase I (GlxI) is a metalloisomerase that is maximally activated by Ni(2+), unlike other known GlxI enzymes which are active with Zn(2+). The metal is coordinated by two aqua lig...

Effects of phenol compounds, glutathione analogues and a diuretic drug on glutathione S-transferase, glutathione reductase and glutathione peroxidase from canine erythrocytes.

Comp. Biochem. Physiol.,. B. 103(4) , 863-7, (1992)

1. Phenol compounds (ellagic acid, quercetin and purpurogallin), glutathione analogues (S-hexylglutathione and S-octylglutathione) and a diuretic drug (ethacrynic acid) were compared for their inhibit...

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