Galanin-Like Peptide (porcine) trifluoroacetate salt

Galanin-Like Peptide (porcine) 是一种 60 个氨基酸的神经肽,首先从猪下丘脑中分离出来。Galanin-Like Peptide (porcine) 对 GALR2 受体具有高亲和力 (IC50 为 0.24 nM),对 GALR1 受体具有较低亲和力 (IC50 为 4.3 nM)。

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[ 相关类别 ]:

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[ 分子式 ]:
C₂₈₁H₄₄₃N₈₁O₇₈

[ 分子量 ]:
6204.1

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Galanin modulates the neural niche to favour perineural invasion in head and neck cancer.

Nat. Commun. 6 , 6885, (2015)

Perineural invasion (PNI) is an indicator of poor survival in multiple cancers. Unfortunately, there is no targeted treatment for PNI since the molecular mechanisms are largely unknown. PNI is an acti...

Galanin-like peptides exert potent vasoactive functions in vivo.

J. Invest. Dermatol. 127(3) , 716-21, (2007)

The cutaneous vasculature plays a key role in the pathophysiology of inflammatory skin diseases. The vascular activity is under the control of the peripheral nervous system that includes locally relea...

Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque.

Endocrinology 143(3) , 755-63, (2002)

Galanin-like peptide (GALP) is a newly discovered hypothalamic neuropeptide, which is regulated by leptin and implicated in the regulation of GnRH secretion in the rodent. We searched the human genome...

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