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N,N-二甲基甘氨酸盐酸盐

N,N-二甲基甘氨酸盐酸盐用途

N、 N-二甲基甘氨酸盐酸盐是甘氨酸(HY-Y0966)衍生物[1]。

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N,N-二甲基甘氨酸盐酸盐名称

[ CAS 号 ]:
2491-06-7

[ 中文名 ]:
N,N-二甲基甘氨酸盐酸盐

[ 英文名 ]:
N,N-Dimethylglycine hydrochloride

[中文别名 ]:

对甲砜基甲苯

[英文别名 ]:

Glycine, N,N-dimethyl-, hydrochloride (1:1)
N,N-Dimethyl glycine hydrochloride
Me2NCH2CO2H hydrochloride
glycine-N',N'-dimethylamide hydrochloride
n,n-dimethylglycine hydrochloride(1:1)
Glycine,N,N-dimethyl-,hydrochloride
Me2NCH2CO2H*HCl
MFCD00012610
N,N-Dimethylglycine hydrochloride
N,N-Dimethylglycine hydrochloride (1:1)

N,N-二甲基甘氨酸盐酸盐生物活性

[ 描述 ]:

N、 N-二甲基甘氨酸盐酸盐是甘氨酸(HY-Y0966)衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

N,N-二甲基甘氨酸盐酸盐物理化学性质

[ 密度 ]:
1.069g/cm3

[ 沸点 ]:
175.2ºC at 760 mmHg

[ 熔点 ]:
189-194 °C(lit.)

[ 分子式 ]:
C₄H₁₀ClNO₂

[ 分子量 ]:
139.581

[ 闪点 ]:
59.8ºC

[ 精确质量 ]:
139.040009

[ PSA ]:
40.54000

[ LogP ]:
0.43460

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.556mmHg at 25°C

[ 储存条件 ]:
室温

[ 水溶解性 ]:
100 g/L (20 ºC)

N,N-二甲基甘氨酸盐酸盐MSDS

N,N-二甲基甘氨酸盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9995000

CHEMICAL NAME :: Glycine, N,N-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 2491-06-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H9-N-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,198,1992

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N,N-二甲基甘氨酸盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
MB9995000

[ 海关编码 ]:
2922499990

N,N-二甲基甘氨酸盐酸盐合成路线

N,N-二甲基甘氨酸盐酸盐上下游产品

N,N-二甲基甘氨酸盐酸盐上游产品

N,N-二甲基甘氨酸盐酸盐下游产品

N,N-二甲基甘氨酸盐酸盐海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

N,N-二甲基甘氨酸盐酸盐文献

Exposure to the proton scavenger glycine under alkaline conditions induces Escherichia coli viability loss.

PLoS ONE 8(3) , e60328, (2013)

Our previous work described a clear loss of Escherichia coli (E. coli) membrane integrity after incubation with glycine or its N-methylated derivatives N-methylglycine (sarcosine) and N,N-dimethylglyc...

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.

Am. J. Clin. Nutr. 97(6) , 1217-27, (2013)

Animal models show that periconceptional supplementation with folic acid, vitamin B-12, choline, and betaine can induce differences in offspring phenotype mediated by epigenetic changes in DNA. In hum...

Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.

Am. J. Clin. Nutr. 97(6) , 1252-9, (2013)

Folate, choline, and betaine participate in homocysteine metabolism. It is not known whether they interact during pregnancy.The objective was to investigate how folate status affects choline, betaine,...

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