12,13-二乙酸佛波醇

12,13-二乙酸佛波醇名称

[ CAS 号 ]:
24928-15-2

[ 中文名 ]:
12,13-二乙酸佛波醇

[ 英文名 ]:
Phorbol 12,13-diacetate

[英文别名 ]:

MFCD00036735
phorbol 12,13-diacetate

12,13-二乙酸佛波醇物理化学性质

[ 密度 ]:
1.34g/cm3

[ 沸点 ]:
585.7ºC at 760 mmHg

[ 分子式 ]:
C₂₄H₃₂O₈

[ 分子量 ]:
448.50600

[ 闪点 ]:
195.4ºC

[ 精确质量 ]:
448.21000

[ PSA ]:
130.36000

[ LogP ]:
1.07170

[ 蒸汽压 ]:
3.69E-16mmHg at 25°C

[ 折射率 ]:
1.592

12,13-二乙酸佛波醇MSDS

12,13-二乙酸佛波醇安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300 + H310 + H330-H315-H319-H335

[ 警示性声明 ]:
P260-P264-P280-P284-P301 + P310-P302 + P350

[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+: Very toxic;

[ 风险声明 (欧洲) ]:
26/27/28-36/37/38

[ 安全声明 (欧洲) ]:
26-27-36/37/39-45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
GZ0651000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

12,13-二乙酸佛波醇合成路线

12,13-二乙酸佛波醇上下游产品

12,13-二乙酸佛波醇上游产品

12,13-二乙酸佛波醇下游产品

12,13-二乙酸佛波醇文献

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

Cell. Signal. 22(3) , 447-56, (2010)

Partitioning of cellular components is a critical mechanism by which cells can regulate their activity. In rod photoreceptors, light induces a large-scale translocation of arrestin from the inner segm...

VNN1, a potential biomarker for pancreatic cancer-associated new-onset diabetes, aggravates paraneoplastic islet dysfunction by increasing oxidative stress.

Cancer Lett. 373 , 241-50, (2016)

In our previous clinical microarray analysis, we were the first to report on Vanin-1 (VNN1) as a novel clinically derived biomarker of pancreatic cancer-associated new-onset diabetes (PCAND). The func...

An improved model of predicting hepatocarcinogenic potential in rats by using gene expression data.

J. Appl. Toxicol. 36 , 296-308, (2016)

Carcinogenicity studies using animals are expensive and time consuming. Therefore, the development of a highly accurate carcinogenicity prediction system to interpret short-term test results would be ...

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