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5,6-diamino-3',6'-bis(diethylamino)spiro[2-benzofuran-3,9'-xanthene]-1-one

用途

5,6-二氨基-N,N,N’,N’-四乙基罗丹明是NO[1]的荧光指示剂。

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名称

[ CAS 号 ]:
261351-45-5

[ 英文名 ]:
5,6-diamino-3',6'-bis(diethylamino)spiro[2-benzofuran-3,9'-xanthene]-1-one

[英文别名 ]:

5,6-Diamino-rhodamine B
5,6-Diamino-N,N,N',N'-tetraethyl-rhodamin
5,6-Diamino-N,N,N',N'-tetraethylrhodamine
DAR-2

生物活性

[ 描述 ]:

5,6-二氨基-N,N,N’,N’-四乙基罗丹明是NO[1]的荧光指示剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kojima H, et al. Fluorescent indicators for nitric oxide based on rhodamine chromophore. Tetrahedron Letters, 2000, 41(1): 69-72.

物理化学性质

[ 密度 ]:
1.31g/cm3

[ 沸点 ]:
736.6ºC at 760 mmHg

[ 分子式 ]:
C₂₈H₃₂N₄O₃

[ 分子量 ]:
472.57900

[ 闪点 ]:
399.3ºC

[ 精确质量 ]:
472.24700

[ PSA ]:
94.05000

[ LogP ]:
6.27380

[ 蒸汽压 ]:
1.47E-21mmHg at 25°C

[ 折射率 ]:
1.684

MSDS

详细MSDS(安全技术说明书)

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

文献

Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophore.

Anal. Chem. 73 , 1967, (2001)

Diaminofluoresceins are widely used for detection and imaging of nitric oxide (NO), but for biological applications, they have the disadvantages that the fluorescence of the fluorescein chromophore is...

H. Kojima et al.

Tetrahedron Lett. 41 , 69, (2000)

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