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N-乙基吡咯烷酮

N-乙基吡咯烷酮用途

【用途一】
主要用于精制油品及生产火药、医药、染料、农药、日化、涂料、耐热树脂等
【用途二】
锂电池,干胶脱脂 ,光致抗蚀剂的剥离剂,涂层展开剂,环氧树脂胶边切除。
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N-乙基吡咯烷酮名称

[ CAS 号 ]:
2687-91-4

[ 中文名 ]:
N-乙基-2-吡咯烷酮

[ 英文名 ]:
N-Ethyl-2-pyrrolidone

[中文别名 ]:

[英文别名 ]:

N-乙基吡咯烷酮物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
203.6±0.0 °C at 760 mmHg

[ 熔点 ]:
< -120 °C

[ 分子式 ]:
C6H11NO

[ 分子量 ]:
113.158

[ 闪点 ]:
76.1±0.0 °C

[ 精确质量 ]:
113.084061

[ PSA ]:
20.31000

[ LogP ]:
0.13

[ 外观性状 ]:
透明液体

[ 蒸汽压 ]:
0.3±0.4 mmHg at 25°C

[ 折射率 ]:
1.465

[ 储存条件 ]:
-70°C

N-乙基吡咯烷酮MSDS

N-乙基吡咯烷酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY5769250
CHEMICAL NAME :
2-Pyrrolidinone, 1-ethyl-
CAS REGISTRY NUMBER :
2687-91-4
BEILSTEIN REFERENCE NO. :
0107971
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H11-N-O
MOLECULAR WEIGHT :
113.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4882359
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N-乙基吡咯烷酮安全信息

[ 符号 ]:

GHS05, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H318-H360D

[ 警示性声明 ]:
P201-P280-P305 + P351 + P338 + P310-P308 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36

[ 安全声明 (欧洲) ]:
S26-S36

[ WGK德国 ]:
1

[ RTECS号 ]:
UY5769250

[ 海关编码 ]:
2933790090

N-乙基吡咯烷酮合成路线

N-乙基吡咯烷酮上下游产品

N-乙基吡咯烷酮海关

[ 海关编码 ]: 2933790090

[ 中文概述 ]:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

N-乙基吡咯烷酮文献

Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.

Dis. Model Mech. 7(12) , 1385-95, (2014)

The complex pathogenesis of Alzheimer's disease (AD) involves multiple contributing factors, including amyloid β (Aβ) peptide accumulation, inflammation and oxidative stress. Effective therapeutic str...

Mercury Reduces the Enzymatic Activity of Neprilysin in Differentiated SH-SY5Y Cells.

Toxicol. Sci. 145 , 128-37, (2015)

Levels of amyloid beta (Aβ) in the central nervous system are regulated by the balance between its synthesis and degradation. Neprilysin (NEP) is associated with Alzheimer's disease (AD) by its abilit...

Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.

Molecular Neurodegeneration 10 , 56, (2015)

Insulin degrading enzyme (IDE) is a major protease of amyloid beta peptide (Aβ), a prominent toxic protein in Alzheimer's disease (AD) pathogenesis. Previous studies suggested that statins promote IDE...


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联系人:夏言

产品详情:[Perfemiker]1-乙基-2-吡咯烷酮,99%


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【N-乙基吡咯烷酮】化源网提供N-乙基吡咯烷酮CAS号2687-91-4,N-乙基吡咯烷酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询N-乙基吡咯烷酮上化源网,专业又轻松。>>电脑版:N-乙基吡咯烷酮

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