Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[a]heptalen-7-yl]-
名称
[ CAS 号 ]:
2826-80-4
[ 英文名 ]:
Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[a]heptalen-7-yl]-
[英文别名 ]:
- 10-methylaminocolchiceine
- N-methyl colchiceinamide
- MB 432
物理化学性质
[ 密度 ]:
1.24g/cm3
[ 沸点 ]:
724.3ºC at 760 mmHg
[ 分子式 ]:
C22H26N2O5
[ 分子量 ]:
398.45200
[ 闪点 ]:
391.9ºC
[ 精确质量 ]:
398.18400
[ PSA ]:
85.89000
[ LogP ]:
3.36860
[ 蒸汽压 ]:
7.79E-21mmHg at 25°C
[ 折射率 ]:
1.594
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GH0878600
- CHEMICAL NAME :
- Colchicine, 10-demethoxy-10-methylamino-
- CAS REGISTRY NUMBER :
- 2826-80-4
- BEILSTEIN REFERENCE NO. :
- 2788038
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H26-N2-O5
- MOLECULAR WEIGHT :
- 398.50
- WISWESSER LINE NOTATION :
- L B677 MV&T&J CO1 DO1 EO1 JMV1 NM1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 759 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981
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CAS号[2826-80-4]化源网提供[Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[a]heptalen-7-yl]-]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[a]heptalen-7-yl]-
标题：2826-80-4_CAS号:2826-80-4_Acetamide,N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylamino)-9-oxobenzo[a]heptalen-7-yl]- - 化源网 地址：https://m.chemsrc.com/mip/cas/2826-80-4_417258.html