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N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)用途

TAPS是一种生物缓冲液,保持溶菌酶天然结构完整,并防止高温下的热变性。TAPS的pKa值为8.1,而连接蛋白通道活性的一半最大值为8.5(pH)[1][2]。

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N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)名称

[ CAS 号 ]:
29915-38-6

[ 中文名 ]:
三羟甲基甲胺基丙磺酸

[ 英文名 ]:
TAPS (buffer)

[中文别名 ]:

[英文别名 ]:

T3A
EINECS 249-954-1
MFCD00007538
TAPS

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)生物活性

[ 描述 ]:

TAPS是一种生物缓冲液,保持溶菌酶天然结构完整,并防止高温下的热变性。TAPS的pKa值为8.1,而连接蛋白通道活性的一半最大值为8.5(pH)[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Pannuru P, et al. The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme. Int J Biol Macromol. 2018 Jun;112:720-727.

[2]. Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9.Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9.

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 熔点 ]:
230-235 °C (dec.)

[ 分子式 ]:
C₇H₁₇NO₆S

[ 分子量 ]:
243.278

[ 闪点 ]:
110 °C

[ 精确质量 ]:
243.077652

[ PSA ]:
135.47000

[ LogP ]:
-2.40

[ 外观性状 ]:
白色结晶粉末。熔点：230-235°C

[ 折射率 ]:
1.561

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents

[ 水溶解性 ]:
Soluble

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)MSDS

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29221980

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)合成路线

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)上下游产品

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)上游产品

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)下游产品

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)海关

[ 海关编码 ]: 29221980

N-三(羟甲基)甲基-3-氨基丙磺酸(TAPS)文献

The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance.

J. Am. Chem. Soc. 137 , 13556-65, (2015)

We report the first direct electrochemical characterization of the impact of oxygen on the hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase: hydrogenase I from Py...

Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration.

Biomaterials 75 , 25-36, (2015)

The use of artificial tissues in regenerative medicine is limited due to hypoxia. As a strategy to overcome this drawback, we have shown that photosynthetic biomaterials can produce and provide oxygen...

Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion.

J. Biol. Chem. 290 , 26638-48, (2015)

The most abundant carbohydrate product of cellulosic biomass pyrolysis is the anhydrosugar levoglucosan (1,6-anhydro-β-d-glucopyranose), which can be converted to glucose 6-phosphate by levoglucosan k...

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