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1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone

名称

[ CAS 号 ]:
30652-12-1

[ 英文名 ]:
1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone

[英文别名 ]:

1-ethyl-3-hydroxy-2-methylpyridin-4-one

物理化学性质

[ 密度 ]:
1.168g/cm3

[ 沸点 ]:
249.5ºC at 760 mmHg

[ 分子式 ]:
C₈H₁₁NO₂

[ 分子量 ]:
153.17800

[ 闪点 ]:
104.7ºC

[ 精确质量 ]:
153.07900

[ PSA ]:
42.23000

[ LogP ]:
0.88220

[ 折射率 ]:
1.546

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7786040

CHEMICAL NAME :: 4(1H)-Pyridinone, 1-ethyl-3-hydroxy-2-methyl-

CAS REGISTRY NUMBER :: 30652-12-1

BEILSTEIN REFERENCE NO. :: 1449942

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H11-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RSUSBS Resuscitation. (Elsevier/North-Holland Biomedical Press, POB 85, Limerick, Ireland) V.1- 1972- Volume(issue)/page/year: 22,139,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 815 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 76,2389,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 gm/kg/52W-I

TOXIC EFFECTS :: Endocrine - changes in spleen weight Related to Chronic Data - death

REFERENCE :: MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 28(Suppl A),81,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 gm/kg/12W-I

TOXIC EFFECTS :: Liver - other changes

REFERENCE :: BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 78,2727,1991

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安全信息

[ 海关编码 ]:
2933399090

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海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%