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7-乙氧基香豆素

7-乙氧基香豆素用途

7-乙氧基香豆素是细胞色素P450(CYP450)的底物,已用于各种CYP的功能表征[1]。

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7-乙氧基香豆素名称

[ CAS 号 ]:
31005-02-4

[ 中文名 ]:
7-乙氧基香豆素

[ 英文名 ]:
7-Ethoxycoumarin

[中文别名 ]:

[英文别名 ]:

7-Ethoxy-1-benzopyran-2-one
7-Ethoxy-2H-chromen-2-one
7-Ethoxycoumarin
7-ethoxychromen-2-one
7-ethoxy-chromen-2-one
Ethylumbelliferone
T66 BOVJ IO2
umbelliferone ethyl ether
ETHOXYCOUMARIN
7-Ethoxy-2H-1-benzopyran-2-one

7-乙氧基香豆素生物活性

[ 描述 ]:

7-乙氧基香豆素是细胞色素P450(CYP450)的底物,已用于各种CYP的功能表征[1]。

[ 相关类别 ]:

研究领域 >> 其他

7-乙氧基香豆素物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
345.0±37.0 °C at 760 mmHg

[ 熔点 ]:
88-90 °C(lit.)

[ 分子式 ]:
C₁₁H₁₀O₃

[ 分子量 ]:
190.195

[ 闪点 ]:
143.1±21.1 °C

[ 精确质量 ]:
190.062988

[ PSA ]:
39.44000

[ LogP ]:
2.31

[ 外观性状 ]:
米色结晶粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.562

[ 储存条件 ]:
室温

7-乙氧基香豆素MSDS

7-乙氧基香豆素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2932209090

7-乙氧基香豆素合成路线

7-乙氧基香豆素上下游产品

7-乙氧基香豆素上游产品

7-乙氧基香豆素下游产品

7-乙氧基香豆素海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

7-乙氧基香豆素文献

Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.

Drug Metab. Dispos. 38(5) , 732-9, (2010)

Human cytochrome P450 (P450) enzymes metabolize a variety of endogenous and xenobiotic compounds, including steroids, drugs, and environmental chemicals. In this study, we examine the possibility that...

A comparison of in vitro ADME properties and pharmacokinetics of azithromycin and selected 15-membered ring macrolides in rodents.

Eur. J. Drug Metab. Pharmacokinet. 39(4) , 263-76, (2014)

The purpose of this study was to evaluate the impact of structural modifications on the 15-membered macrolactone ring and/or substituents on the in vitro ADME properties and in vivo pharmacokinetic (P...

In vivo indirect measurement of cytochrome P450-associated activities in freshwater gastropod molluscs.

Environ. Toxicol. 25(6) , 545-53, (2010)

The cytochrome P450 (CYP) system is widely distributed across phyla and plays a key role in the metabolism of xenobiotic compounds. However, most studies on CYP system were developed on vertebrates an...

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