4-苯二甲酰亚氨基丁酸

4-苯二甲酰亚氨基丁酸用途

4-(N-Phthalimidoyl)butanoic acid (化合物 FB) 是一种半抗原,其间隔臂末端含有羧基,适合与蛋白质的游离胺基反应。4-(N-Phthalimidoyl)butanoic acid 可与载体蛋白结合,应用于抗原的设计。

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4-苯二甲酰亚氨基丁酸名称

[ CAS 号 ]:
3130-75-4

[ 中文名 ]:
4-(1,3-二氧代异吲哚啉-2-基)丁酸

[ 英文名 ]:
4-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)butanoic acid

[中文别名 ]:

[英文别名 ]:

MFCD00196079
4-(1,3-dioxoisoindol-2-yl)butanoic acid
4-Phthalimidobutyric Acid

4-苯二甲酰亚氨基丁酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

[参考文献]

[1]. Mercader JV, et al. Development of monoclonal ELISAs for azinphos-methyl. 1. Hapten synthesis and antibody production. J Agric Food Chem. 1999 Mar;47(3):1276-84.

4-苯二甲酰亚氨基丁酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
442.1±28.0 °C at 760 mmHg

[ 熔点 ]:
119-121ºC

[ 分子式 ]:
C₁₂H₁₁NO₄

[ 分子量 ]:
233.220

[ 闪点 ]:
221.2±24.0 °C

[ 精确质量 ]:
233.068802

[ PSA ]:
74.68000

[ LogP ]:
1.58

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.605

[ 储存条件 ]:
室温

4-苯二甲酰亚氨基丁酸MSDS

详细MSDS(安全技术说明书)

4-苯二甲酰亚氨基丁酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NR3459000

CHEMICAL NAME :: 2-Isoindolinebutyric acid, 1,3-dioxo-

CAS REGISTRY NUMBER :: 3130-75-4

BEILSTEIN REFERENCE NO. :: 0208243

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H11-N-O4

MOLECULAR WEIGHT :: 233.24

WISWESSER LINE NOTATION :: T56 BVNVJ C3VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 327 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 27,805,1989 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 400 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 28,680,1973

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4-苯二甲酰亚氨基丁酸安全信息

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 海关编码 ]:
2925190090

4-苯二甲酰亚氨基丁酸合成路线

详细合成路线

4-苯二甲酰亚氨基丁酸上下游产品

4-苯二甲酰亚氨基丁酸上游产品

4-苯二甲酰亚氨基丁酸下游产品

4-苯二甲酰亚氨基丁酸海关

[ 海关编码 ]: 2925190090

[ 中文概述 ]:
2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%