醉椒素

Kavain是一类从 Piper methysticum 中分离出来的卡瓦酸内酯,对动物和人类具有抗焦虑和镇静作用。Kavain 可以正调控 GABAA 受体。

[ 描述 ]:

[体外研究]

[参考文献]

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
432.6±45.0 °C at 760 mmHg

[ 熔点 ]:
142-148ºC

[ 分子式 ]:
C₁₄H₁₄O₃

[ 分子量 ]:
230.259

[ 闪点 ]:
184.6±23.3 °C

[ 精确质量 ]:
230.094299

[ PSA ]:
35.53000

[ LogP ]:
1.69

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.565

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

Fatal kavalactone intoxication by suicidal intravenous injection.

Forensic Sci. Int. 249 , e7-11, (2015)

Kavalactones are a group of compounds found in kava, a beverage or extract prepared from the rhizome of the kava plant (Piper methysticum). Traditionally kava extracts have been used for their anxioly...

Kavalactones fail to inhibit alcohol dehydrogenase in vitro.

Phytomedicine 13(3) , 192-5, (2006)

In recent years, Kava kava (Piper methysticum, Forst. f., Piperaceae), a folkloric beverage and popular herbal remedy, has been implicated in a number of liver failure cases. Many hypotheses as to the...

Kavalactones Yangonin and Methysticin induce apoptosis in human hepatocytes (HepG2) in vitro.

Phytother Res. 25(3) , 417-23, (2011)

While cases of severe kava hepatotoxicity have been reported, studies examining the toxicity of individual kavalactones are limited. The present study examined the in vitro hepatotoxicity of kavain, m...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：(±)-醉椒素

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥1768.0/20mg

联系人：刘佳

产品详情：(±)-醉椒素

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公司名：广东翁江化学试剂有限公司

区域：韶关市翁源县

价格：
￥8000.0/1g

联系人：朱丽丹

产品详情：DL-醉椒素

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