美西律

美西律用途

【用途一】
用作抗心律失常药。
点击显示

美西律名称

[ CAS 号 ]:
31828-71-4

[ 中文名 ]:
美西律

[ 英文名 ]:
1-(2,6-Dimethylphenoxy)-2-propanamine

[英文别名 ]:

美西律物理化学性质

[ 密度 ]:
0.979 g/cm3

[ 沸点 ]:
271.5ºC at 760 mmHg

[ 熔点 ]:
203-205ºC

[ 分子式 ]:
C11H17NO

[ 分子量 ]:
179.25900

[ 闪点 ]:
112.2ºC

[ 精确质量 ]:
179.13100

[ PSA ]:
35.25000

[ LogP ]:
2.72970

[ 外观性状 ]:
powder | white

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
ethanol: 50 mg/mL

美西律毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR9300000
CHEMICAL NAME :
Ethylamine, 1-methyl-2-(2,6-xylyloxy)-
CAS REGISTRY NUMBER :
31828-71-4
LAST UPDATED :
199703
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C11-H17-N-O
MOLECULAR WEIGHT :
179.29
WISWESSER LINE NOTATION :
ZY1&1OR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
63 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - nausea or vomiting
REFERENCE :
PMESAJ Postgraduate Medical Journal, Supplement. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1949- Volume(issue)/page/year: 53(Suppl 1),134,1977
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
349 mg/kg/4D-I
TOXIC EFFECTS :
Blood - thrombocytopenia
REFERENCE :
AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 100,162,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
41 mg/kg
TOXIC EFFECTS :
Toxic effects not yet reviewed
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5116974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DECRDP Drugs under Experimental and Clinical Research. (Bioscience Ediprint, Blvd. James-Fazy 13, 1201 Geneva 1, Switzerland) V.1- 1977- Volume(issue)/page/year: 13,21,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
114 mg/kg
TOXIC EFFECTS :
Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 21,370,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 41,1130,1991
点击显示

美西律安全信息

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
UN 3249

[ WGK德国 ]:
3

[ RTECS号 ]:
KR9300000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2922299090

美西律上下游产品

美西律上游产品

美西律下游产品

美西律制备

【方法一】
由2，6-二甲基苯酚出发。
点击显示

美西律海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

相关药品：

推荐生产厂家/供应商：

暂无推荐供应商。请联系客服获知如何成为推荐供应商。

相关化合物

【美西律】化源网提供美西律CAS号31828-71-4，美西律MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询美西律上化源网，专业又轻松。>>电脑版：美西律

标题：美西律_用途_密度_熔点_美西律CAS号【31828-71-4】_化源网 地址：https://m.chemsrc.com/mip/cas/31828-71-4_88495.html