3-(三氟甲基)异氰酸苯酯
3-(三氟甲基)异氰酸苯酯用途
3-三氟甲基苯基异氰酸酯是除草剂氟草隆的中间体。
【用途二】
主要用作医药，农药中间体。
3-(三氟甲基)异氰酸苯酯名称
[ CAS 号 ]:
329-01-1
[ 中文名 ]:
3-(三氟甲基)异氰酸苯酯
[ 英文名 ]:
3-(Trifluoromethyl)phenyl isocyanate
[中文别名 ]:
- 间三氟甲基苯异氰酸酯
- α,α,α-三氟间甲苯基异氰酸酯
- 3-三氟甲苯基异氰酸酯
- 异氰酸-3-(三氟甲基)苯酯
- 3-三氟甲基苯基异氰酸酯
- 3-(三氟甲基)苯基异氰酸酯
- 3-(三氟甲基)苯基异氰酸苯酯
- 三氟甲苯异氰酸酯
[英文别名 ]:
- α,α,α-Trifluoro-m-tolyl Isocyanate
- 3-Isocyanatobenzotrifluoride
- 3-trifluoromethylisocyanate
- a,a,a-Trifluoro-m-tolyl isocyanate
- 3-CF3phenylisocyanate
- 3-(Trifluoromethyl)phenyl Isocyanate
- Isocyanobenzotrifluoride
- m-trifluoromethylphenyl isocyanate
- MFCD00002020
- alpha,alpha,alpha-Trifluoro-m-tolyl isocyanate
3-(三氟甲基)异氰酸苯酯物理化学性质
[ 密度 ]:
1.336
[ 沸点 ]:
54 ºC (11 mmHg)
[ 熔点 ]:
-26 °C
[ 分子式 ]:
C8H4F3NO
[ 分子量 ]:
187.119
[ 闪点 ]:
58 ºC
[ 精确质量 ]:
187.024506
[ PSA ]:
29.43000
[ LogP ]:
3.95
[ 外观性状 ]:
无色至淡黄色液体
[ 蒸汽压 ]:
2.0±0.3 mmHg at 25°C
[ 折射率 ]:
1.467-1.469
[ 储存条件 ]:
库房通风低温干燥,与氧化剂,酸类,食品分开储运
[ 水溶解性 ]:
可溶于：甲苯
3-(三氟甲基)异氰酸苯酯MSDS
3-(三氟甲基)异氰酸苯酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NR0200000
- CHEMICAL NAME :
- Isocyanic acid, (m-trifluoromethylphenyl) ester
- CAS REGISTRY NUMBER :
- 329-01-1
- BEILSTEIN REFERENCE NO. :
- 0744880
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C8-H4-F3-N-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 975 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 328 mg/m3/1H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - deviated nasal septum Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535360
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 975 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3300 mg/m3
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 871 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,2204,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 478 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11300 ug/m3/4H/17W-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Cardiac - other changes Liver - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11300 ug/m3/2H/11W-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Cardiac - other changes Liver - other changes
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(3),53,1976
3-(三氟甲基)异氰酸苯酯安全信息
[ 符号 ]:
GHS02, GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H302-H315-H317-H330-H334-H335
[ 警示性声明 ]:
P260-P280-P284-P310
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
T+:Verytoxic;
[ 风险声明 (欧洲) ]:
R21/22;R26;R36/37/38;R42
[ 安全声明 (欧洲) ]:
S23-S28-S45-S36/37/39-S28A-S26-S36/37-S22-S9
[ 危险品运输编码 ]:
UN 3384 6.1/PG 1
[ WGK德国 ]:
2
[ RTECS号 ]:
NR0200000
[ 包装等级 ]:
II
[ 危险类别 ]:
6.1
[ 海关编码 ]:
2929109000
3-(三氟甲基)异氰酸苯酯上下游产品
3-(三氟甲基)异氰酸苯酯上游产品
3-(三氟甲基)异氰酸苯酯下游产品
3-(三氟甲基)异氰酸苯酯制备
其制备方法是在反应瓶中加入3-三氟甲基苯胺与氯苯搅拌，使其混合溶解，冷却至0～10℃，通入干燥氯化氢使其饱和，然后再加入N，N-二异丁基氯甲基酰胺，加热至50℃保温30 min，然后再通入光气，通入一定量光气后反应结束，通入氮气赶尽物料中的氯化氢和余量的光气，赶光后再将物料蒸馏并脱溶得成品。
3-(三氟甲基)异氰酸苯酯海关
[ 海关编码 ]: 2929109000
[ 中文概述 ]:
2929109000. 其他异氰酸酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
3-(三氟甲基)异氰酸苯酯文献
Antimicrob. Agents Chemother. 54 , 846-51, (2010)
The activity of the new cephalosporin CXA-101 (CXA), previously designated FR264205, was evaluated against a collection of 236 carbapenem-resistant P. aeruginosa isolates, including 165 different clon...
Effects of ring substituents on enantioselective recognition of amino alcohols and acids in uryl-based binol receptors. Nandhakumar R, et al.Tetrahedron 64(33) , 7704-8, (2008)
The Interaction of Amphotericin B with Cholesteryl Trifluoromethylphenyl-carbamate. Vijan LE, et al.
Rev. Chim. (Bucharest, Rom.) 60(2) , 142-6, (2009)
相关化工产品/化学物质：
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价格：
联系人：徐经理
产品详情：3-(三氟甲基)苯基异氰酸酯
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区域：上海市奉贤区
价格：
￥608.0/25ml
￥178.0/5ml
联系人：刘佳
产品详情：3-(三氟甲基)苯基异氰酸酯
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥360.0/5g
￥1599.0/25g
￥99.0/1g
￥5899.0/100g
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相关化合物
【3-(三氟甲基)异氰酸苯酯】化源网提供3-(三氟甲基)异氰酸苯酯CAS号329-01-1，3-(三氟甲基)异氰酸苯酯MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询3-(三氟甲基)异氰酸苯酯上化源网，专业又轻松。>>电脑版：3-(三氟甲基)异氰酸苯酯
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