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Bikaverin

Bikaverin用途

Bikaverin (Lycopersin) 是一种由不同真菌产生的略带红色的色素,对某些原生动物和真菌具有抗生素特性。

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Bikaverin名称

[ CAS 号 ]:
33390-21-5

[ 英文名 ]:
Bikaverin

[英文别名 ]:

Lycopersin
Bikaverin

Bikaverin生物活性

[ 描述 ]:

Bikaverin (Lycopersin) 是一种由不同真菌产生的略带红色的色素,对某些原生动物和真菌具有抗生素特性。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[体外研究]

化学上,比卡维林(Lycopersin)是一种具有四环苯并黄酮类结构的聚酮类化合物,是由特定的I类多功能聚酮合酶的活性和随后由单加氧酶和O-甲基转移酶引入的基团修饰而成的[1]。比卡韦林是一种红色聚酮类色素,由藤仓赤霉素和大量赤霉素产生[2]。

[参考文献]

[1]. Limón MC, et al. Bikaverin production and applications. Appl Microbiol Biotechnol. 2010;87(1):21-29.

[2]. Lale GJ, Gadre RV. Production of bikaverin by a Fusarium fujikuroi mutant in submerged cultures. AMB Express. 2016;6(1):34.

Bikaverin物理化学性质

[ 密度 ]:
1.61g/cm3

[ 沸点 ]:
719.8ºC at 760mmHg

[ 分子式 ]:
C₂₀H₁₄O₈

[ 分子量 ]:
382.32000

[ 闪点 ]:
263.3ºC

[ 精确质量 ]:
382.06900

[ PSA ]:
123.27000

[ LogP ]:
2.58370

[ 折射率 ]:
1.711

BikaverinMSDS

Bikaverin毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DM2901000

CHEMICAL NAME :: 10H-Benzo(b)xanthene-7,10,12-trione, 6,11-dihydroxy-3,8-dimethoxy-1-methyl-

CAS REGISTRY NUMBER :: 33390-21-5

BEILSTEIN REFERENCE NO. :: 0358013

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C20-H14-O8

MOLECULAR WEIGHT :: 382.34

WISWESSER LINE NOTATION :: T E6 C666 BO FV IV MVJ DQ GO1 KQ O1 QO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Cells - not otherwise specified

DOSE/DURATION :: 4200 ug/L

REFERENCE :: NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 22,335,1975

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Bikaverin安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301

[ 警示性声明 ]:
P301 + P310

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ RTECS号 ]:
DM2901000

Bikaverin合成路线

Bikaverin上下游产品

Bikaverin上游产品

Bikaverin下游产品

Bikaverin文献

Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans.

J. Appl. Microbiol. 104(3) , 692-8, (2008)

To isolate and identify antioomycete substances from Fusarium oxysporum EF119 against Phytophthora infestans and to investigate their antimicrobial activities against various plant pathogenic bacteria...

United States Department of Agriculture-Agricultural Research Service studies on polyketide toxins of Fusarium oxysporum f sp vasinfectum: potential targets for disease control.

Pest Manag. Sci. 59(6-7) , 736-47, (2003)

A group of 133 isolates of the cotton wilt pathogen Fusarium oxysporum Schlecht f sp vasinfectum (Atk) Sny & Hans, representing five races and 20 vegetative compatibility groups within race 1 were use...

GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.

Mycologia 100(5) , 701-9, (2008)

Fusarium verticillioides (teleomorph Gibberella moniliformis) is an ascomycete known to produce a variety of secondary metabolites, including fumonisins, fusaric acid and bikaverin. These metabolites ...

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