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丽春红3R

丽春红3R用途

胭脂红3R是一种偶氮染料,可用作食品着色剂[1]。

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丽春红3R名称

[ CAS 号 ]:
3564-09-8

[ 中文名 ]:
丽春红3R

[ 英文名 ]:
PONCEAU 3R

[中文别名 ]:

[英文别名 ]:

AKA502
FDandC Rot Nr.1
MFCD00036432
ponceaurn
fdcred1
EINECS 222-638-0
afredno1
dandcred15
ponceau3rn
cifood6

丽春红3R生物活性

[ 描述 ]:

胭脂红3R是一种偶氮染料,可用作食品着色剂[1]。

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Hartman CP, et al. Production of a mutagen from ponceau 3R by a human intestinal anaerobe. Infect Immun. 1979 Mar;23(3):686-9.

丽春红3R物理化学性质

[ 分子式 ]:
C₁₉H₁₆N₂Na₂O₇S₂

[ 分子量 ]:
494.45

[ 精确质量 ]:
494.01900

[ PSA ]:
176.11000

[ LogP ]:
5.85580

[ 储存条件 ]:
室温，干燥，密封

丽春红3RMSDS

详细MSDS(安全技术说明书)

丽春红3R毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QJ6650000

CHEMICAL NAME :: 2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-((2,4,5-trimethylphenyl)azo)-, disodium salt

CAS REGISTRY NUMBER :: 3564-09-8

LAST UPDATED :: 199709

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C19-H16-N2-O7-S2.2Na

MOLECULAR WEIGHT :: 494.47

WISWESSER LINE NOTATION :: L66J BNUNR B1 D1 E1& CQ DSWQ HSWQ &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 730 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1640 gm/kg/65W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1140 gm/kg/68W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 gm/kg/24W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 1701 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,223,1987 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,199,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,199,1975 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83806 No. of Facilities: 131 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 827 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83806 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 36 (estimated) No. of Female Employees: 16 (estimated)

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丽春红3R安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335-H351

[ 警示性声明 ]:
P261-P281-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S22-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
QJ6650000

丽春红3R文献

Localization of gelatinolytic activity can be detected in breast cancer tissues by film in situ zymography.

Breast Cancer 8(2) , 111-5, (2001)

Extracellular matrix-degrading proteinases secreted by malignant tumor cells have been thought to play an essential role in the processes of invasion and metastasis. However, existence and localizatio...

Configurational changes in rat liver nuclear chromatin caused by azo dyes.

Food Chem. Toxicol. 22(5) , 337-44, (1984)

The effects of azo dyes on the chromatin configuration of isolated rat-liver nuclei were examined by electron microscopy for elucidation of the mechanism of dye-stimulated in vitro RNA synthesis. Suns...

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