十六醇
十六醇用途
十六醇名称
[ CAS 号 ]:
36653-82-4
[ 中文名 ]:
鲸蜡醇
[ 英文名 ]:
1-Hexadecanol
[中文别名 ]:
[英文别名 ]:
- EINECS 253-149-0
- 1-Hexadecanol
- HEXADECANOL
- Loxanwax SK
- Adol 52NF
- 1-Hexanedecanol
- Cetyl alcohol,Palmityl alcohol
- hexadecyl alcohol
- Cachalot C 51
- cetyle alcohol
十六醇生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
十六醇物理化学性质
[ 密度 ]:
0.8±0.1 g/cm3
[ 沸点 ]:
310.9±5.0 °C at 760 mmHg
[ 熔点 ]:
49-51 °C
[ 分子式 ]:
C16H34O
[ 分子量 ]:
242.441
[ 闪点 ]:
135.0±0.0 °C
[ 精确质量 ]:
242.260971
[ PSA ]:
20.23000
[ LogP ]:
7.25
[ 外观性状 ]:
白色叶片状结晶。
[ 蒸汽密度 ]:
8.34 (vs air)
[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C
[ 折射率 ]:
1.448
[ 储存条件 ]:
2-8°C
[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, strong acids.
[ 水溶解性 ]:
insoluble
十六醇MSDS
十六醇毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MM0225000
- CHEMICAL NAME :
- 1-Hexadecanol
- CAS REGISTRY NUMBER :
- 36653-82-4
- BEILSTEIN REFERENCE NO. :
- 1748475
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C16-H34-O
- MOLECULAR WEIGHT :
- 242.50
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human
- REFERENCE :
- 85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976," Drill, V.A., and P. Lazar, eds., New York, Academic Press, Inc. 1977 Volume(issue)/page/year: -,127,1977
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human - man
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,493,1973
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,493,1973
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,683,1978
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Cardiac - other changes Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 7(3),359,1988
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2220 mg/m3/6H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 7(3),359,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,683,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,683,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,683,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,493,1973
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4635,1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80588 No. of Facilities: 11045 (estimated) No. of Industries: 66 No. of Occupations: 70 No. of Employees: 161543 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80588 No. of Facilities: 11292 (estimated) No. of Industries: 67 No. of Occupations: 102 No. of Employees: 421768 (estimated) No. of Female Employees: 324449 (estimated)
十六醇安全信息
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi
[ 风险声明 (欧洲) ]:
R38:Irritating to the skin. R36/37/38:Irritating to eyes, respiratory system and skin .
[ 安全声明 (欧洲) ]:
S22-S24/25-S37
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
-
[ RTECS号 ]:
MM0225000
[ 海关编码 ]:
2905170000
十六醇合成路线
十六醇上下游产品
十六醇上游产品
十六醇下游产品
十六醇制备
1.该品最早由鲸蜡水解得到的。工业上可由油脂还原，或用硼氢化钠还原十六酰氯制得。
2.由鲸蜡水解得到十六酸后再还原，或用油脂直接还原。也可以用硼氢化钠还原十六酰氯制得。
3.以油脂为原料，经高压加氢或用金属钠还原法制取。
4.将甲苯和金属钠共热至金属钠完全熔化，停止加热，快速搅拌至钠呈散砂状并使温度降至60℃。然后加入十六酸乙酯的无水乙醇溶液 （ 每摩尔十六酸乙酯加无水乙醇300ml） ，接着，再加相等量的无水乙醇，控制加料速度，以高效回流冷凝器内全回流为宜。
反应式为：
当反应平稳后，油浴加热回流至钠完全溶尽。然后用水蒸气蒸馏除去甲苯和乙醇，剩余物用热水洗涤三次，再用乙醚分别萃取冷却后的油状物和水洗液，抽得醚层依次用水、碳酸钠溶液、水洗涤，并用硫酸镁干燥脱水，蒸去乙醚，最后，进行减压蒸馏，控制压力为1600Pa，收集178～182℃馏分，即为成品。
5.采用皂化法和还原法。皂化法以软脂酸鲸蜡酯为原料,用氢氧化钠皂化而得。还原法以棕榈酸为原料,进行还原反应而得。
十六醇海关
[ 海关编码 ]: 2905170000
[ 中文概述 ]:
2905170000 十二醇、十六醇及十八醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最低关税:7.0%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 包装
[ Summary ]:
2905170000 hexadecan-1-ol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:7.0%。General tariff:30.0%
十六醇文献
Int. J. Cosmet. Sci. 36(5) , 494-504, (2014)
The present investigation is based on the formulation of water-in-oil (w/o) cream preparations of ascorbic acid (AA) at pH 4-6 using different emollients and humectants.The preparations were stored in...
Antioxidant activity of protocatechuates evaluated by DPPH, ORAC, and CAT methods.Food Chem. 194 , 749-57, (2015)
Hibiscus sabdariffa L. is a worldwide consumed plant, principally after infusion of its dried sepals and calyces, which are usually discarded. Nevertheless, they represent a potential source of natura...
Evaluation of injection methods for fast, high peak capacity separations with low thermal mass gas chromatography.J. Chromatogr. A. 1392 , 82-90, (2015)
Low thermal mass gas chromatography (LTM-GC) was evaluated for rapid, high peak capacity separations with three injection methods: liquid, headspace solid phase micro-extraction (HS-SPME), and direct ...
相关化工产品/化学物质：
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公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：十六醇
公司名：南通润丰石油化工有限公司
区域：南通市崇川区
价格：
￥需询单/1kg
￥需询单/1ton
联系人：曹经理
产品详情：十六醇
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥108.0/500g
联系人：刘佳
产品详情：十六醇
公司名：上海脉铂医药科技有限公司
区域：上海市嘉定区
价格：
￥489.0/1g
￥389.0/50mg
￥需询单/1g
￥需询单/1g
联系人：李先生
产品详情：1-Hexadecanol
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥37.0/500g
￥142.0/2500g
￥41.0/100g
￥86.0/500g
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相关化合物
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