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异菌脲

异菌脲用途

Iprodione 是一种二甲酰亚胺类杀菌剂,具有高度特异性的作用,能够通过产生自由氧自由基 (ROS) 引起氧化损伤,但它似乎没有物种选择性。

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异菌脲名称

[ CAS 号 ]:
36734-19-7

[ 中文名 ]:
异菌脲

[ 英文名 ]:
Iprodione

[中文别名 ]:

[英文别名 ]:

5-24-05-00201 (Beilstein Handbook Reference)
26019 rp
rovrol
ROVRAL
mrc910
ROVER
KIDAN
MFCD00055353
Iprodione
EINECS 253-178-9

异菌脲生物活性

[ 描述 ]:

Iprodione 是一种二甲酰亚胺类杀菌剂,具有高度特异性的作用,能够通过产生自由氧自由基 (ROS) 引起氧化损伤,但它似乎没有物种选择性。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

[参考文献]

[1]. Radice S, et al. Effect of iprodione, a dicarboximide fungicide, on primary cultured rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat Toxicol. 2001;54(1-2):51-58.

异菌脲物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
481.1±55.0 °C at 760 mmHg

[ 熔点 ]:
130-134 °C(lit.)

[ 分子式 ]:
C₁₃H₁₃Cl₂N₃O₃

[ 分子量 ]:
330.167

[ 闪点 ]:
244.7±31.5 °C

[ 精确质量 ]:
329.033386

[ PSA ]:
69.72000

[ LogP ]:
2.22

[ 外观性状 ]:
奶油色至无色,无气味的粉末

[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C

[ 折射率 ]:
1.645

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
0.0013 g/100 mL

异菌脲MSDS

详细MSDS(安全技术说明书)

异菌脲毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI8870000

CHEMICAL NAME :: 1-Imidazolidinecarboxamide, 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-

CAS REGISTRY NUMBER :: 36734-19-7

BEILSTEIN REFERENCE NO. :: 0895003

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C13-H13-Cl2-N3-O3

MOLECULAR WEIGHT :: 330.19

WISWESSER LINE NOTATION :: T5NVNV EHJ AVMY1&1 CR CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,501,1991

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3300 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,501,1991

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 30,124,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 30,124,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,501,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C173,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 930 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,501,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 10400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,501,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1181 mg/kg/7D-C

TOXIC EFFECTS :: Gastrointestinal - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 31,479,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

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异菌脲安全信息

[ 符号 ]:

GHS08, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H351-H410

[ 警示性声明 ]:
P273-P281-P501

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R40;R50/53

[ 安全声明 (欧洲) ]:
S36/37-S60-S61-S36-S26-S16

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
NI8870000

[ 危险类别 ]:
9.0

[ 海关编码 ]:
2933290011

异菌脲上下游产品

异菌脲上游产品

异菌脲下游产品

异菌脲制备

甘氦酸(NH2CH2COOH)或酷与3,5一二氯异氰酸苯酷反应，生成3.5一二氯苯基)醚踞乙酸(或酷)，按着环化，得3-(3,5一二氯苯基)乙内醚二滚乙，熔点190 C;，待用。将4.6g ( 0.0l 9mol)异丙基异氰酸酷和J归睬(0 .054mo1)二乙胺的混合物，添加到llg (0.045mo1) 3-(3,5一二氯苯基)内醚踞、150m工_丙酮洛液中。加热回流30min后冷却，减压脱洛，残留物用石油醚（沸点50～70℃，250Ml）洗净，经异丙醚重结晶，得11g异菌脲，收率74.2%，熔点136℃。

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异菌脲海关

[ 海关编码 ]: 2933290011

[ 中文概述 ]:
2933290011 异菌脲退税率:9.0% 监管条件:S(进出口农药登记证明)

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2933290011 3-(3,5-dichlorophenyl)-n-isopropyl-2,4-dioxoimidazolidine-1-carboxamide

异菌脲文献

Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.

Talanta 85(3) , 1500-7, (2011)

Pesticides residues in aquatic ecosystems are an environmental concern which requires efficient analytical methods. In this study, we proposed a generic method for the quantification of 13 pesticides ...

Ultraviolet-vis degradation of iprodione and estimation of the acute toxicity of its photodegradation products.

J. Chromatogr. A. 1371 , 146-53, (2014)

The UV-vis photodegradation of iprodione in water was investigated with a high pressure mercury lamp photoreactor. Five photoproducts of iprodione were characterized by LC-HR-MS/MS and isotopic labeli...

Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.

Int. J. Food Microbiol. 162(3) , 237-44, (2013)

Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the ...

更多文献

异菌脲

异菌脲用途

异菌脲名称

异菌脲生物活性

异菌脲物理化学性质

异菌脲MSDS

详细MSDS(安全技术说明书)

异菌脲毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

异菌脲安全信息

异菌脲上下游产品

异菌脲上游产品

异菌脲下游产品

异菌脲制备

异菌脲海关

异菌脲文献

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