米洛沙星
米洛沙星名称
米洛沙星物理化学性质
[ 密度 ]:
1.6±0.1 g/cm3
[ 沸点 ]:
460.9±55.0 °C at 760 mmHg
[ 熔点 ]:
264° (dec)
[ 分子式 ]:
C12H9NO6
[ 分子量 ]:
263.203
[ 闪点 ]:
232.5±31.5 °C
[ 精确质量 ]:
263.042999
[ PSA ]:
86.99000
[ LogP ]:
1.34
[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C
[ 折射率 ]:
1.689
米洛沙星毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JI5060000
- CHEMICAL NAME :
- 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-5-methoxy-8-oxo-
- CAS REGISTRY NUMBER :
- 37065-29-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H9-N-O6
- MOLECULAR WEIGHT :
- 263.22
- WISWESSER LINE NOTATION :
- T C566 DO FO JN MV EHJ JO1 LVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 36400 mg/kg/26W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in uterine weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 413 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1650 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3300 mg/kg
- SEX/DURATION :
- female 7-17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8100 mg/kg
- SEX/DURATION :
- female 17-22 day(s) after conception lactating female 21 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - physical
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 140 ug/L
- REFERENCE :
- AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 17,763,1980
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米洛沙星安全信息
[ 海关编码 ]:
2934999090
米洛沙星合成路线
米洛沙星上下游产品
米洛沙星上游产品
米洛沙星下游产品
米洛沙星海关
[ 海关编码 ]: 2934999090
[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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