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环丁基甲酸

环丁基甲酸用途

【用途一】
用于有机合成

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环丁基甲酸名称

[ CAS 号 ]:
3721-95-7

[ 中文名 ]:
环丁基甲酸

[ 英文名 ]:
Cyclo-butyl formic acid

[中文别名 ]:

[英文别名 ]:

cyclobutane carboxylic acid
EINECS 223-072-7
cyclobutylcarboxylic acid
MFCD00001323
Cyclo-butyl formic acid
cyclobutanoic acid
Cyclobutanecarboxylic acid

环丁基甲酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
195.3±8.0 °C at 760 mmHg

[ 熔点 ]:
−7.5 °C(lit.)

[ 分子式 ]:
C₅H₈O₂

[ 分子量 ]:
100.116

[ 闪点 ]:
83.9±0.0 °C

[ 精确质量 ]:
100.052429

[ PSA ]:
37.30000

[ LogP ]:
0.65

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
0.2±0.8 mmHg at 25°C

[ 折射率 ]:
1.502

[ 储存条件 ]:
室温

[ 水溶解性 ]:
水溶性：微溶

环丁基甲酸MSDS

环丁基甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU1335000

CHEMICAL NAME :: Cyclobutanecarboxylic acid

CAS REGISTRY NUMBER :: 3721-95-7

BEILSTEIN REFERENCE NO. :: 1816777

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H8-O2

MOLECULAR WEIGHT :: 100.13

WISWESSER LINE NOTATION :: L4TJ AVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1270 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,85,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1270 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,85,1969

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环丁基甲酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H312-H314-H332

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S23-S24/25

[ 危险品运输编码 ]:
3265

[ WGK德国 ]:
3

[ RTECS号 ]:
GU1335000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2942000000

环丁基甲酸合成路线

环丁基甲酸上下游产品

环丁基甲酸上游产品

环丁基甲酸下游产品

环丁基甲酸制备

将环丁烷-1,1-二羧酸放入蒸馏装置加热，在160℃左右脱羧基放出二氧化碳，然后加热蒸馏，收集189-195℃馏分即为粗品，重新蒸馏，得成品环丁烷羧酸。产率86%-91%。

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环丁基甲酸海关

[ 海关编码 ]: 2916209090

[ 中文概述 ]:
2916209090 其他（环烷、环烯、环萜烯）一元羧酸（包括酸酐、酰卤化物，过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

环丁基甲酸文献

Circuit formation and function in the olfactory bulb of mice with reduced spontaneous afferent activity.

J. Neurosci. 35(1) , 146-60, (2015)

The type of neuronal activity required for circuit development is a matter of significant debate. We addressed this issue by analyzing the topographic organization of the olfactory bulb in transgenic ...

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs.

FASEB J. 26 , 4951-65, (2012)

When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are use...

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环丁基甲酸

环丁基甲酸用途

环丁基甲酸名称

环丁基甲酸物理化学性质

环丁基甲酸MSDS

详细MSDS(安全技术说明书)

环丁基甲酸毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

环丁基甲酸安全信息

环丁基甲酸合成路线

详细合成路线

环丁基甲酸上下游产品

环丁基甲酸上游产品

环丁基甲酸下游产品

环丁基甲酸制备

环丁基甲酸海关

环丁基甲酸文献

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