O,O-diacetyl-4-hydroxyaminoquinoline 1-oxide

名称

[ CAS 号 ]:
38539-23-0

[ 英文名 ]:
O,O-diacetyl-4-hydroxyaminoquinoline 1-oxide

物理化学性质

[ 密度 ]:
1.3g/cm3

[ 沸点 ]:
357.9ºC at 760mmHg

[ 分子式 ]:
C₁₃H₁₂N₂O₄

[ 分子量 ]:
260.24500

[ 闪点 ]:
170.2ºC

[ 精确质量 ]:
260.08000

[ PSA ]:
73.02000

[ LogP ]:
2.71910

[ 折射率 ]:
1.596

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂、酸类分开存放

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB4800000

CHEMICAL NAME :: Quinoline, 1,4-dihydro-1-acetoxy-4-hydroxyamino-, acetate (ester)

CAS REGISTRY NUMBER :: 38539-23-0

LAST UPDATED :: 199410

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H13-N2-O4

MOLECULAR WEIGHT :: 261.28

WISWESSER LINE NOTATION :: T66 BN EHJ BOV1 EMVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 mg/kg/2W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 50 mg/L

REFERENCE :: IGSBAL Igaku to Seibutsugaku. Medicine and Biology. (c/o Ogato Igaku Kagaku Kenkyusho, 2-3-5 Bakuro-cho, Nihonbashi, Chuo-ku, Tokyo 103, Japan) V.1- 1942- Volume(issue)/page/year: 85,127,1972

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