4-(羟氨基)喹啉 N-氧化物
4-(羟氨基)喹啉 N-氧化物名称
[ CAS 号 ]:
4637-56-3
[ 中文名 ]:
4-羟基氨基喹啉 N-氧化物
[ 英文名 ]:
4-Hydroxyaminoquinoline-1-oxide
[中文别名 ]:
[英文别名 ]:
- 4-Hydroxyaminoquinoline-1-oxide
- 4-hydroxyaminoquinoline 1-oxide
- 4haqo
- 4-Quinolinamine, N-hydroxy-, 1-oxide
- hydroxyaminoquinolineoxide
- Wln: T66 bnj bo emq
- N-(4-Quinolyl)hydroxylamine 1'-Oxide
- Quinoline, 4- (hydroxyamino)-, 1-oxide
- 4-HYDROXYLAMINOQUINOLINE1-OXIDE
- 4-(HydroxyaMino)quinoline N-Oxide
4-(羟氨基)喹啉 N-氧化物物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
425.6±55.0 °C at 760 mmHg
[ 熔点 ]:
214ºC
[ 分子式 ]:
C9H8N2O2
[ 分子量 ]:
176.172
[ 闪点 ]:
211.2±31.5 °C
[ 精确质量 ]:
176.058578
[ PSA ]:
57.72000
[ LogP ]:
0.00
[ 外观性状 ]:
固体;White to Amber powder to lump
[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C
[ 折射率 ]:
1.651
[ 储存条件 ]:
室温，干燥
4-(羟氨基)喹啉 N-氧化物MSDS
4-(羟氨基)喹啉 N-氧化物毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB9800000
- CHEMICAL NAME :
- Quinoline, 4-(hydroxyamino)-, 1-oxide
- CAS REGISTRY NUMBER :
- 4637-56-3
- BEILSTEIN REFERENCE NO. :
- 0154476
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 73
- MOLECULAR FORMULA :
- C9-H8-N2-O2
- MOLECULAR WEIGHT :
- 176.19
- WISWESSER LINE NOTATION :
- T66 BNJ BO EMQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Liver - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg/9W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1350 mg/kg/18W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 mg/kg/60D-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg/9W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg/9W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Musculoskeletal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 16 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- DNA inhibition
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- DNA adduct
- TYPE OF TEST :
- Unscheduled DNA synthesis
MUTATION DATA
- TYPE OF TEST :
- DNA adduct
- TEST SYSTEM :
- Bird - chicken Embryo
- DOSE/DURATION :
- 200 umol/L
- REFERENCE :
- CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 47,123,1983 *** REVIEWS *** TOXICOLOGY REVIEW RRCRBU Recent Results in Cancer Research. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1965- Volume(issue)/page/year: 34,32,1971 TOXICOLOGY REVIEW APLMAS Archives of Pathology and Laboratory Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-5(2), 1926-28; V.100- 1976- Volume(issue)/page/year: 107,54,1983
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4-(羟氨基)喹啉 N-氧化物安全信息
[ 危害码 (欧洲) ]:
T
[ 风险声明 (欧洲) ]:
45-46-25-37/38-41-68
[ 安全声明 (欧洲) ]:
53-26-36/37/39-45
[ RTECS号 ]:
VB9800000
[ 海关编码 ]:
2933499090
4-(羟氨基)喹啉 N-氧化物合成路线
4-(羟氨基)喹啉 N-氧化物上下游产品
4-(羟氨基)喹啉 N-氧化物上游产品
4-(羟氨基)喹啉 N-氧化物下游产品
4-(羟氨基)喹啉 N-氧化物海关
[ 海关编码 ]: 2933499090
[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
推荐生产厂家/供应商：
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥2961.0/5g
￥279.0/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁李高志
产品详情：4-(羟氨基)喹啉 N-氧化物
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥349.0/250mg
￥880.0/1g
联系人：夏言
产品详情：[Perfemiker]4-(羟氨基)喹啉 N-氧化物,≥97%(T)
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标题：4-(羟氨基)喹啉 N-氧化物_MSDS_密度_熔点_CAS号【4637-56-3】_化源网 地址：https://m.chemsrc.com/mip/cas/4637-56-3_756656.html